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Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD.
Benjamin JT, Plosa EJ, Sucre JM, van der Meer R, Dave S, Gutor S, Nichols DS, Gulleman PM, Jetter CS, Han W, Xin M, Dinella PC, Catanzarite A, Kook S, Dolma K, Lal CV, Gaggar A, Blalock JE, Newcomb DC, Richmond BW, Kropski JA, Young LR, Guttentag SH, Blackwell TS. Benjamin JT, et al. Among authors: guttentag sh. J Clin Invest. 2021 Jan 4;131(1):e139481. doi: 10.1172/JCI139481. J Clin Invest. 2021. PMID: 33108351 Free PMC article.
β1 Integrin regulates adult lung alveolar epithelial cell inflammation.
Plosa EJ, Benjamin JT, Sucre JM, Gulleman PM, Gleaves LA, Han W, Kook S, Polosukhin VV, Haake SM, Guttentag SH, Young LR, Pozzi A, Blackwell TS, Zent R. Plosa EJ, et al. Among authors: guttentag sh. JCI Insight. 2020 Jan 30;5(2):e129259. doi: 10.1172/jci.insight.129259. JCI Insight. 2020. PMID: 31873073 Free PMC article.
Age-determined expression of priming protease TMPRSS2 and localization of SARS-CoV-2 in lung epithelium.
Schuler BA, Habermann AC, Plosa EJ, Taylor CJ, Jetter C, Negretti NM, Kapp ME, Benjamin JT, Gulleman P, Nichols DS, Braunstein LZ, Hackett A, Koval M, Guttentag SH, Blackwell TS, Webber SA, Banovich NE; Vanderbilt COVID-19 Consortium Cohort; Human Cell Atlas Biological Network; Kropski JA, Sucre JM. Schuler BA, et al. Among authors: guttentag sh. J Clin Invest. 2021 Jan 4;131(1):e140766. doi: 10.1172/JCI140766. J Clin Invest. 2021. PMID: 33180746 Free PMC article.
Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes.
Kook S, Qi A, Wang P, Meng S, Gulleman P, Young LR, Guttentag SH. Kook S, et al. Among authors: guttentag sh. Am J Respir Cell Mol Biol. 2018 May;58(5):566-574. doi: 10.1165/rcmb.2017-0324MA. Am J Respir Cell Mol Biol. 2018. PMID: 29190429 Free PMC article.
Successful Establishment of Primary Type II Alveolar Epithelium with 3D Organotypic Coculture.
Sucre JMS, Jetter CS, Loomans H, Williams J, Plosa EJ, Benjamin JT, Young LR, Kropski JA, Calvi CL, Kook S, Wang P, Gleaves L, Eskaros A, Goetzl L, Blackwell TS, Guttentag SH, Zijlstra A. Sucre JMS, et al. Among authors: guttentag sh. Am J Respir Cell Mol Biol. 2018 Aug;59(2):158-166. doi: 10.1165/rcmb.2017-0442MA. Am J Respir Cell Mol Biol. 2018. PMID: 29625013 Free PMC article.
Hyperoxia Injury in the Developing Lung Is Mediated by Mesenchymal Expression of Wnt5A.
Sucre JMS, Vickers KC, Benjamin JT, Plosa EJ, Jetter CS, Cutrone A, Ransom M, Anderson Z, Sheng Q, Fensterheim BA, Ambalavanan N, Millis B, Lee E, Zijlstra A, Königshoff M, Blackwell TS, Guttentag SH. Sucre JMS, et al. Among authors: guttentag sh. Am J Respir Crit Care Med. 2020 May 15;201(10):1249-1262. doi: 10.1164/rccm.201908-1513OC. Am J Respir Crit Care Med. 2020. PMID: 32023086 Free PMC article.
A single-cell atlas of mouse lung development.
Negretti NM, Plosa EJ, Benjamin JT, Schuler BA, Habermann AC, Jetter CS, Gulleman P, Bunn C, Hackett AN, Ransom M, Taylor CJ, Nichols D, Matlock BK, Guttentag SH, Blackwell TS, Banovich NE, Kropski JA, Sucre JMS. Negretti NM, et al. Among authors: guttentag sh. Development. 2021 Dec 15;148(24):dev199512. doi: 10.1242/dev.199512. Epub 2021 Dec 20. Development. 2021. PMID: 34927678 Free PMC article.
Age-determined expression of priming protease TMPRSS2 and localization of SARS-CoV-2 infection in the lung epithelium.
Schuler BA, Christian Habermann A, Plosa EJ, Taylor CJ, Jetter C, Kapp ME, Benjamin JT, Gulleman P, Nichols DS, Braunstein LZ, Hackett A, Koval M, Guttentag SH, Blackwell TS; Vanderbilt COVID-19 Consortium Cohort; Webber SA, Banovich NE, Kropski JA, Sucre JMS; HCA Lung Biological Network. Schuler BA, et al. Among authors: guttentag sh. bioRxiv [Preprint]. 2020 Aug 3:2020.05.22.111187. doi: 10.1101/2020.05.22.111187. bioRxiv. 2020. Update in: J Clin Invest. 2021 Jan 4;131(1):140766. doi: 10.1172/JCI140766 PMID: 32511364 Free PMC article. Updated. Preprint.
71 results