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RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo.
Alkasalias T, Alexeyenko A, Hennig K, Danielsson F, Lebbink RJ, Fielden M, Turunen SP, Lehti K, Kashuba V, Madapura HS, Bozoky B, Lundberg E, Balland M, Guvén H, Klein G, Gad AK, Pavlova T. Alkasalias T, et al. Among authors: guven h. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1413-E1421. doi: 10.1073/pnas.1621161114. Epub 2017 Feb 7. Proc Natl Acad Sci U S A. 2017. PMID: 28174275 Free PMC article.
Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth.
Alexeyenko A, Alkasalias T, Pavlova T, Szekely L, Kashuba V, Rundqvist H, Wiklund P, Egevad L, Csermely P, Korcsmaros T, Guven H, Klein G. Alexeyenko A, et al. Among authors: guven h. J Exp Clin Cancer Res. 2015 Jun 18;34(1):62. doi: 10.1186/s13046-015-0178-x. J Exp Clin Cancer Res. 2015. PMID: 26081588 Free PMC article.
Decreased decorin expression in the tumor microenvironment.
Bozoky B, Savchenko A, Guven H, Ponten F, Klein G, Szekely L. Bozoky B, et al. Among authors: guven h. Cancer Med. 2014 Jun;3(3):485-91. doi: 10.1002/cam4.231. Epub 2014 Mar 17. Cancer Med. 2014. PMID: 24634138 Free PMC article.
Safety analysis of ex vivo-expanded NK and NK-like T cells administered to cancer patients: a phase I clinical study.
Barkholt L, Alici E, Conrad R, Sutlu T, Gilljam M, Stellan B, Christensson B, Guven H, Björkström NK, Söderdahl G, Cederlund K, Kimby E, Aschan J, Ringdén O, Ljunggren HG, Dilber MS. Barkholt L, et al. Among authors: guven h. Immunotherapy. 2009 Sep;1(5):753-64. doi: 10.2217/imt.09.47. Immunotherapy. 2009. PMID: 20636021 Clinical Trial.
192 results