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Learning from failure--rationale and design for a study about discontinuation of randomized trials (DISCO study).
Kasenda B, von Elm EB, You J, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl J, Stegert M, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla S, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Rosenthal R, Schandelmaier S, Sun X, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Bucher HC, Guyatt GH, Briel M. Kasenda B, et al. Among authors: guyatt gh. BMC Med Res Methodol. 2012 Aug 28;12:131. doi: 10.1186/1471-2288-12-131. BMC Med Res Methodol. 2012. PMID: 22928744 Free PMC article.
An observational study found that authors of randomized controlled trials frequently use concealment of randomization and blinding, despite the failure to report these methods.
Devereaux PJ, Choi PT, El-Dika S, Bhandari M, Montori VM, Schünemann HJ, Garg AX, Busse JW, Heels-Ansdell D, Ghali WA, Manns BJ, Guyatt GH. Devereaux PJ, et al. Among authors: guyatt gh. J Clin Epidemiol. 2004 Dec;57(12):1232-6. doi: 10.1016/j.jclinepi.2004.03.017. J Clin Epidemiol. 2004. PMID: 15617948
Validity of composite end points in clinical trials.
Montori VM, Permanyer-Miralda G, Ferreira-González I, Busse JW, Pacheco-Huergo V, Bryant D, Alonso J, Akl EA, Domingo-Salvany A, Mills E, Wu P, Schünemann HJ, Jaeschke R, Guyatt GH. Montori VM, et al. Among authors: guyatt gh. BMJ. 2005 Mar 12;330(7491):594-6. doi: 10.1136/bmj.330.7491.594. BMJ. 2005. PMID: 15761002 Free PMC article. Review.
Randomized trials stopped early for benefit: a systematic review.
Montori VM, Devereaux PJ, Adhikari NK, Burns KE, Eggert CH, Briel M, Lacchetti C, Leung TW, Darling E, Bryant DM, Bucher HC, Schünemann HJ, Meade MO, Cook DJ, Erwin PJ, Sood A, Sood R, Lo B, Thompson CA, Zhou Q, Mills E, Guyatt GH. Montori VM, et al. Among authors: guyatt gh. JAMA. 2005 Nov 2;294(17):2203-9. doi: 10.1001/jama.294.17.2203. JAMA. 2005. PMID: 16264162 Review.
1,057 results