Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1988 1
1989 4
1990 2
1991 2
1993 5
1994 4
1995 6
1996 6
1997 3
1998 1
1999 4
2000 5
2001 1
2002 2
2003 3
2004 13
2005 11
2006 12
2007 14
2008 14
2009 12
2010 27
2011 25
2012 27
2013 26
2014 29
2015 25
2016 32
2017 29
2018 37
2019 36
2020 39
2021 41
2022 63
2023 52
2024 63
2025 60
2026 11

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

668 results

Results by year

Filters applied: . Clear all
The following term was not found in PubMed: penthyllum
Page 1
Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): a randomized, double-blind, placebo-controlled trial.
Park SH, Huh TL, Kim SY, Oh MR, Tirupathi Pichiah PB, Chae SW, Cha YS. Park SH, et al. Obesity (Silver Spring). 2014 Jan;22(1):63-71. doi: 10.1002/oby.20539. Epub 2013 Sep 5. Obesity (Silver Spring). 2014. PMID: 23804546 Free article. Clinical Trial.
OBJECTIVE: The effects of actiponin was investigated, a heat-processed Gynostemma pentaphyllum extract, on body weight, fat loss, and metabolic markers of Korean participants in a 12-week, randomized, double-blind, placebo-controlled clinical trial. ...
OBJECTIVE: The effects of actiponin was investigated, a heat-processed Gynostemma pentaphyllum extract, on body weight, fat loss, and …
Progress in the Medicinal Value, Bioactive Compounds, and Pharmacological Activities of Gynostemma pentaphyllum.
Su C, Li N, Ren R, Wang Y, Su X, Lu F, Zong R, Yang L, Ma X. Su C, et al. Molecules. 2021 Oct 15;26(20):6249. doi: 10.3390/molecules26206249. Molecules. 2021. PMID: 34684830 Free PMC article. Review.
Gynostemma pentaphyllum (Thunb.) Makino (GP), also named Jiaogulan in Chinese, was known to people for its function in both health care and disease treatment. ...
Gynostemma pentaphyllum (Thunb.) Makino (GP), also named Jiaogulan in Chinese, was known to people for its function in both health ca
Saponins derived from Gynostemma pentaphyllum regulate triglyceride and cholesterol metabolism and the mechanisms: A review.
Xie P, Luo HT, Pei WJ, Xiao MY, Li FF, Gu YL, Piao XL. Xie P, et al. J Ethnopharmacol. 2024 Jan 30;319(Pt 1):117186. doi: 10.1016/j.jep.2023.117186. Epub 2023 Sep 16. J Ethnopharmacol. 2024. PMID: 37722515 Review.
ETHNOPHARMACOLOGICAL RELEVANCE: Gynostemma pentaphyllum (Thunb.) Makino (G. pentaphyllum) can be used for both medicinal and tea and has lipid-lowering properties. ...CONCLUSION: To date, more than 328 saponins have been isolated and identified in Gynostemma. Furthe …
ETHNOPHARMACOLOGICAL RELEVANCE: Gynostemma pentaphyllum (Thunb.) Makino (G. pentaphyllum) can be used for both medicinal and tea and …
The Role of Gynostemma pentaphyllum in Regulating Hyperlipidemia.
Li Y, Ouyang Q, Li X, Alolgal RN, Fan Y, Sun Y, Gong H, Xiao P, Ma G. Li Y, et al. Am J Chin Med. 2023;51(4):953-978. doi: 10.1142/S0192415X23500441. Epub 2023 Apr 28. Am J Chin Med. 2023. PMID: 37129524
This study aims to investigate the effectiveness and underlying mechanisms of Gynostemma pentaphyllum (GP) in the treatment of hyperlipidemia. First, a meta-analysis was performed to determine the lipid-lowering effects of GP. Thereafter, hyperlipidemia was induced in mice …
This study aims to investigate the effectiveness and underlying mechanisms of Gynostemma pentaphyllum (GP) in the treatment of hyperl …
Gynostemma pentaphyllum Extract Alleviates NASH in Mice: Exploration of Inflammation and Gut Microbiota.
Jiang FY, Yue SR, Tan YY, Tang N, Xu YS, Zhang BJ, Mao YJ, Xue ZS, Lu AP, Liu BC, Wang RR. Jiang FY, et al. Nutrients. 2024 Jun 6;16(11):1782. doi: 10.3390/nu16111782. Nutrients. 2024. PMID: 38892715 Free PMC article.
In this study, we explored the therapeutic effect of Gynostemma pentaphyllum extract (GPE), a Chinese herbal extract, on methionine- and choline-deficient (MCD) diet-induced NASH mice. ...
In this study, we explored the therapeutic effect of Gynostemma pentaphyllum extract (GPE), a Chinese herbal extract, on methionine- …
The Complete Chloroplast Genomes of Gynostemma Reveal the Phylogenetic Relationships of Species within the Genus.
Gan J, Li Y, Tang D, Guo B, Li D, Cao F, Sun C, Yu L, Yan Z. Gan J, et al. Genes (Basel). 2023 Apr 17;14(4):929. doi: 10.3390/genes14040929. Genes (Basel). 2023. PMID: 37107687 Free PMC article.
The chloroplast genomes of seven species of the genus Gynostemma were sequenced and annotated, of which the genomes of Gynostemma simplicifolium, Gynostemma guangxiense and Gynostemma laxum were sequenced and annotated for the first time. ...Phylogenet …
The chloroplast genomes of seven species of the genus Gynostemma were sequenced and annotated, of which the genomes of Gynostemma
Triterpenoids from the genus Gynostemma: Chemistry and pharmacological activities.
Nguyen NH, Ha TKQ, Yang JL, Pham HTT, Oh WK. Nguyen NH, et al. J Ethnopharmacol. 2021 Mar 25;268:113574. doi: 10.1016/j.jep.2020.113574. Epub 2020 Nov 10. J Ethnopharmacol. 2021. PMID: 33186700 Review.
MATERIALS AND METHODS: The relevant literature on the genus Gynostemma was gathered from secondary databases (Web of Science and PubMed), books, and official websites. ...However, the promising preliminary data of other Gynostemma species indicated the research pote …
MATERIALS AND METHODS: The relevant literature on the genus Gynostemma was gathered from secondary databases (Web of Science and PubM …
Phytochemistry, bioactivities and application of Gynostemma pentaphyllum polysaccharide: A review.
Hu X, Wang W, Zhang D, Tian X, Zhang A, Xu J, Feng F, Li W, Kikuchi T, Zhang J. Hu X, et al. Int J Biol Macromol. 2025 Sep;322(Pt 1):144964. doi: 10.1016/j.ijbiomac.2025.144964. Epub 2025 Jun 4. Int J Biol Macromol. 2025. PMID: 40480562 Review.
Gynostemma pentaphyllum (Thunb.) Makino (GP) (Cucurbitaceae), commonly considered as a folk remedy, has a long history of use in many parts of Asia. Polysaccharides are one of the main components of GP and possess antioxidant, antitumor, anti-inflammatory, immunomodulatory
Gynostemma pentaphyllum (Thunb.) Makino (GP) (Cucurbitaceae), commonly considered as a folk remedy, has a long history of use in many
Hypoglycemic triterpenes from Gynostemma pentaphyllum.
Wang J, Ha TKQ, Shi YP, Oh WK, Yang JL. Wang J, et al. Phytochemistry. 2018 Nov;155:171-181. doi: 10.1016/j.phytochem.2018.08.008. Epub 2018 Aug 18. Phytochemistry. 2018. PMID: 30130690
To search for bioactive gypenosides and their analogues, a saponin enriched fraction and its hydrolyzate from Gynostemma pentaphyllum were phytochemically investigated. Fractionation by diverse chromatographic methods, including HPLC, Sephadex LH-20, silica gel, and C18 re …
To search for bioactive gypenosides and their analogues, a saponin enriched fraction and its hydrolyzate from Gynostemma pentaphyllum …
New Dammarane-type Saponins from Gynostemma pentaphyllum.
Chen PY, Chang CC, Huang HC, Zhang LJ, Liaw CC, Lin YC, Nguyen NL, Vo TH, Cheng YY, Morris-Natschke SL, Lee KH, Kuo YH. Chen PY, et al. Molecules. 2019 Apr 8;24(7):1375. doi: 10.3390/molecules24071375. Molecules. 2019. PMID: 30965662 Free PMC article.
Six new dammarane-type saponins, gypenosides CP1-6 (16), along with 19 known compounds 7-25, were isolated and characterized from the aerial parts of Gynostemma pentaphyllum. Among these compounds, eight dammarane-type saponins, 2, 5, 6, 7, 11, 12, 13, and 15, exhibited th …
Six new dammarane-type saponins, gypenosides CP1-6 (16), along with 19 known compounds 7-25, were isolated and characterized from the aerial …
668 results