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Streptococcal wall component OK432 restores sensitivity of non-obese diabetic (NOD) thymocytes to apoptotic signals.
Decallonne B, Overbergh L, Casteels KM, Gysemans C, Bouillon R, Mathieu C. Decallonne B, et al. Diabetologia. 2000 Oct;43(10):1302-8. doi: 10.1007/s001250051526. Diabetologia. 2000. PMID: 11079749
By RT-PCR analysis of a panel of apoptosis-related genes in thymocytes we showed a down-regulation of anti-apoptotic Bcl-xL and c-myc by OK432 treatment. ...
By RT-PCR analysis of a panel of apoptosis-related genes in thymocytes we showed a down-regulation of anti-apoptotic Bcl-xL and c-myc …
Immunomodulatory properties of a 1,25(OH)(2) vitamin D(3) analog combined with IFNbeta in an animal model of syngeneic islet transplantation.
van Etten E, Gysemans C, Verstuyf A, Bouillon R, Mathieu C. van Etten E, et al. Transplant Proc. 2001 May;33(3):2319. doi: 10.1016/s0041-1345(01)02007-3. Transplant Proc. 2001. PMID: 11377545 No abstract available.
A combination of KH1060, a vitamin D(3) analogue, and cyclosporin prevents early graft failure and prolongs graft survival of xenogeneic islets in nonobese diabetic mice.
Gysemans C, Waer M, Laureys J, Bouillon R, Mathieu C. Gysemans C, et al. Transplant Proc. 2001 May;33(3):2365. doi: 10.1016/s0041-1345(01)02022-x. Transplant Proc. 2001. PMID: 11377560 No abstract available.
Dual role of interferon-gamma signalling pathway in sensitivity of pancreatic beta cells to immune destruction.
Gysemans CA, Pavlovic D, Bouillon R, Eizirik DL, Mathieu C. Gysemans CA, et al. Diabetologia. 2001 May;44(5):567-74. doi: 10.1007/s001250051662. Diabetologia. 2001. PMID: 11380074
Islet graft survival rate of IFN-gammaR-/- and 129/Sv/Ev islets, when transplanted in alloxan-diabetic BALB/c recipients, was comparable (12.0 +/- 1.9 days vs 12.9 +/- 2.3 days, NS). Allograft rejection, however, of IRF-1-/- islets by BALB/c recipients occurred more …
Islet graft survival rate of IFN-gammaR-/- and 129/Sv/Ev islets, when transplanted in alloxan-diabetic BALB/c recipients, was compara …
In vitro and in vivo analysis of the immune system of vitamin D receptor knockout mice.
Mathieu C, Van Etten E, Gysemans C, Decallonne B, Kato S, Laureys J, Depovere J, Valckx D, Verstuyf A, Bouillon R. Mathieu C, et al. J Bone Miner Res. 2001 Nov;16(11):2057-65. doi: 10.1359/jbmr.2001.16.11.2057. J Bone Miner Res. 2001. PMID: 11697802
Treatment of autoimmune diabetes recurrence in non-obese diabetic mice by mouse interferon-beta in combination with an analogue of 1alpha,25-dihydroxyvitamin-D3.
Gysemans C, Van Etten E, Overbergh L, Verstuyf A, Waer M, Bouillon R, Mathieu C. Gysemans C, et al. Clin Exp Immunol. 2002 May;128(2):213-20. doi: 10.1046/j.1365-2249.2002.01825.x. Clin Exp Immunol. 2002. PMID: 11985511 Free PMC article.
Prevention of primary non-function of islet xenografts in autoimmune diabetic NOD mice by anti-inflammatory agents.
Gysemans C, Stoffels K, Giulietti A, Overbergh L, Waer M, Lannoo M, Feige U, Mathieu C. Gysemans C, et al. Diabetologia. 2003 Aug;46(8):1115-23. doi: 10.1007/s00125-003-1154-0. Epub 2003 Jul 17. Diabetologia. 2003. PMID: 12879250
Vitamin D deficiency in early life accelerates Type 1 diabetes in non-obese diabetic mice.
Giulietti A, Gysemans C, Stoffels K, van Etten E, Decallonne B, Overbergh L, Bouillon R, Mathieu C. Giulietti A, et al. Diabetologia. 2004 Mar;47(3):451-462. doi: 10.1007/s00125-004-1329-3. Epub 2004 Jan 31. Diabetologia. 2004. PMID: 14758446
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