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H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway.
Eberhardt M, Dux M, Namer B, Miljkovic J, Cordasic N, Will C, Kichko TI, de la Roche J, Fischer M, Suárez SA, Bikiel D, Dorsch K, Leffler A, Babes A, Lampert A, Lennerz JK, Jacobi J, Martí MA, Doctorovich F, Högestätt ED, Zygmunt PM, Ivanovic-Burmazovic I, Messlinger K, Reeh P, Filipovic MR. Eberhardt M, et al. Among authors: hogestatt ed. Nat Commun. 2014 Jul 15;5:4381. doi: 10.1038/ncomms5381. Nat Commun. 2014. PMID: 25023795 Free PMC article.
Pungent products from garlic activate the sensory ion channel TRPA1.
Bautista DM, Movahed P, Hinman A, Axelsson HE, Sterner O, Högestätt ED, Julius D, Jordt SE, Zygmunt PM. Bautista DM, et al. Among authors: hogestatt ed. Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12248-52. doi: 10.1073/pnas.0505356102. Epub 2005 Aug 15. Proc Natl Acad Sci U S A. 2005. PMID: 16103371 Free PMC article.
Zygmunt PM, Högestätt ED. Zygmunt PM, et al. Among authors: hogestatt ed. Handb Exp Pharmacol. 2014;222:583-630. doi: 10.1007/978-3-642-54215-2_23. Handb Exp Pharmacol. 2014. PMID: 24756722 Review.
TRPV1-mediated itch in seasonal allergic rhinitis.
Alenmyr L, Högestätt ED, Zygmunt PM, Greiff L. Alenmyr L, et al. Among authors: hogestatt ed. Allergy. 2009 May;64(5):807-10. doi: 10.1111/j.1398-9995.2009.01937.x. Epub 2009 Feb 13. Allergy. 2009. PMID: 19220220
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