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Dose effects of transfected c-Ha-rasVal 12 oncogene in transformed cell clones.
Sistonen L, Keski-Oja J, Ulmanen I, Hölttä E, Wikgren BJ, Alitalo K. Sistonen L, et al. Exp Cell Res. 1987 Feb;168(2):518-30. doi: 10.1016/0014-4827(87)90024-3. Exp Cell Res. 1987. PMID: 3803452
c-Jun activation-dependent tumorigenic transformation induced paradoxically by overexpression or block of S-adenosylmethionine decarboxylase.
Paasinen-Sohns A, Kielosto M, Kääriäinen E, Eloranta T, Laine A, Jänne OA, Birrer MJ, Hölttä E. Paasinen-Sohns A, et al. J Cell Biol. 2000 Nov 13;151(4):801-10. doi: 10.1083/jcb.151.4.801. J Cell Biol. 2000. PMID: 11076965 Free PMC article.
Cell transformation by ornithine decarboxylase is associated with phosphorylation of the transactivation domain of c-Jun.
Hölttä E, Paasinen-Sohns A, Povelainen M, Järvinen K, Ravanko K, Kangas A. Hölttä E, et al. Biochem Soc Trans. 1998 Nov;26(4):621-7. doi: 10.1042/bst0260621. Biochem Soc Trans. 1998. PMID: 10047794 No abstract available.
Involvement of CPP32/Caspase-3 in c-Myc-induced apoptosis.
Kangas A, Nicholson DW, Hölttä E. Kangas A, et al. Oncogene. 1998 Jan 22;16(3):387-98. doi: 10.1038/sj.onc.1201779. Oncogene. 1998. PMID: 9467964
We also found that the expression of p53, p21waf1/cip1, Bcl-2, Bax, Bcl-xL, Bad and cyclins D1, E, A and B did not show any significant changes following c-Myc induction. ...
We also found that the expression of p53, p21waf1/cip1, Bcl-2, Bax, Bcl-xL, Bad and cyclins D1, E, A and B did not show any significa …
Cells transformed by ODC, c-Ha-ras and v-src exhibit MAP kinase/Erk-independent constitutive phosphorylation of Sos, Raf and c-Jun activation domain, and reduced PDGF receptor expression.
Paasinen-Sohns A, Hölttä E. Paasinen-Sohns A, et al. Oncogene. 1997 Oct 16;15(16):1953-66. doi: 10.1038/sj.onc.1201366. Oncogene. 1997. PMID: 9365242
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