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74 results
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Plasticity of tumour and immune cells: a source of heterogeneity and a cause for therapy resistance?
Hölzel M, Bovier A, Tüting T. Hölzel M, et al. Nat Rev Cancer. 2013 May;13(5):365-76. doi: 10.1038/nrc3498. Epub 2013 Mar 28. Nat Rev Cancer. 2013. PMID: 23535846 Review.
In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche.
Breitbach M, Kimura K, Luis TC, Fuegemann CJ, Woll PS, Hesse M, Facchini R, Rieck S, Jobin K, Reinhardt J, Ohneda O, Wenzel D, Geisen C, Kurts C, Kastenmüller W, Hölzel M, Jacobsen SEW, Fleischmann BK. Breitbach M, et al. Among authors: holzel m. Cell Stem Cell. 2018 Feb 1;22(2):262-276.e7. doi: 10.1016/j.stem.2018.01.008. Cell Stem Cell. 2018. PMID: 29451855
Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis.
Young A, Ngiow SF, Madore J, Reinhardt J, Landsberg J, Chitsazan A, Rautela J, Bald T, Barkauskas DS, Ahern E, Huntington ND, Schadendorf D, Long GV, Boyle GM, Hölzel M, Scolyer RA, Smyth MJ. Young A, et al. Among authors: holzel m. Cancer Res. 2017 Sep 1;77(17):4684-4696. doi: 10.1158/0008-5472.CAN-17-0393. Epub 2017 Jun 26. Cancer Res. 2017. PMID: 28652244
RAS and PD-L1: A Masters' Liaison in Cancer Immune Evasion.
Glodde N, Hölzel M. Glodde N, et al. Among authors: holzel m. Immunity. 2017 Dec 19;47(6):1007-1009. doi: 10.1016/j.immuni.2017.12.001. Immunity. 2017. PMID: 29262340
A stochastic model for immunotherapy of cancer.
Baar M, Coquille L, Mayer H, Hölzel M, Rogava M, Tüting T, Bovier A. Baar M, et al. Among authors: holzel m. Sci Rep. 2016 Apr 11;6:24169. doi: 10.1038/srep24169. Sci Rep. 2016. PMID: 27063839 Free PMC article.
Inflammation-Induced Plasticity in Melanoma Therapy and Metastasis.
Hölzel M, Tüting T. Hölzel M, et al. Trends Immunol. 2016 Jun;37(6):364-374. doi: 10.1016/ Epub 2016 Apr 15. Trends Immunol. 2016. PMID: 27151281 Review.
Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy.
Glodde N, Bald T, van den Boorn-Konijnenberg D, Nakamura K, O'Donnell JS, Szczepanski S, Brandes M, Eickhoff S, Das I, Shridhar N, Hinze D, Rogava M, van der Sluis TC, Ruotsalainen JJ, Gaffal E, Landsberg J, Ludwig KU, Wilhelm C, Riek-Burchardt M, Müller AJ, Gebhardt C, Scolyer RA, Long GV, Janzen V, Teng MWL, Kastenmüller W, Mazzone M, Smyth MJ, Tüting T, Hölzel M. Glodde N, et al. Among authors: holzel m. Immunity. 2017 Oct 17;47(4):789-802.e9. doi: 10.1016/j.immuni.2017.09.012. Immunity. 2017. PMID: 29045907
MAPK Signaling and Inflammation Link Melanoma Phenotype Switching to Induction of CD73 during Immunotherapy.
Reinhardt J, Landsberg J, Schmid-Burgk JL, Ramis BB, Bald T, Glodde N, Lopez-Ramos D, Young A, Ngiow SF, Nettersheim D, Schorle H, Quast T, Kolanus W, Schadendorf D, Long GV, Madore J, Scolyer RA, Ribas A, Smyth MJ, Tumeh PC, Tüting T, Hölzel M. Reinhardt J, et al. Among authors: holzel m. Cancer Res. 2017 Sep 1;77(17):4697-4709. doi: 10.1158/0008-5472.CAN-17-0395. Epub 2017 Jun 26. Cancer Res. 2017. PMID: 28652246
Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.
Falletta P, Sanchez-Del-Campo L, Chauhan J, Effern M, Kenyon A, Kershaw CJ, Siddaway R, Lisle R, Freter R, Daniels MJ, Lu X, Tüting T, Middleton M, Buffa FM, Willis AE, Pavitt G, Ronai ZA, Sauka-Spengler T, Hölzel M, Goding CR. Falletta P, et al. Among authors: holzel m. Genes Dev. 2017 Jan 1;31(1):18-33. doi: 10.1101/gad.290940.116. Epub 2017 Jan 17. Genes Dev. 2017. PMID: 28096186 Free PMC article.
Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells.
Knappe N, Novak D, Weina K, Bernhardt M, Reith M, Larribere L, Hölzel M, Tüting T, Gebhardt C, Umansky V, Utikal J. Knappe N, et al. Among authors: holzel m. Stem Cells. 2016 Apr;34(4):832-46. doi: 10.1002/stem.2284. Epub 2016 Jan 19. Stem Cells. 2016. PMID: 26753613
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