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A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation.
Frick R, Høydahl LS, Petersen J, du Pré MF, Kumari S, Berntsen G, Dewan AE, Jeliazkov JR, Gunnarsen KS, Frigstad T, Vik ES, Llerena C, Lundin KEA, Yaqub S, Jahnsen J, Gray JJ, Rossjohn J, Sollid LM, Sandlie I, Løset GÅ. Frick R, et al. Among authors: hoydahl ls. Sci Immunol. 2021 Aug 20;6(62):eabg4925. doi: 10.1126/sciimmunol.abg4925. Sci Immunol. 2021. PMID: 34417258 Free PMC article.
Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation.
Lau C, Gunnarsen KS, Høydahl LS, Andersen JT, Berntzen G, Pharo A, Lindstad JK, Ludviksen JK, Brekke OL, Barratt-Due A, Nielsen EW, Stokes CR, Espevik T, Sandlie I, Mollnes TE. Lau C, et al. Among authors: hoydahl ls. J Immunol. 2013 Nov 1;191(9):4769-77. doi: 10.4049/jimmunol.1301653. Epub 2013 Sep 23. J Immunol. 2013. PMID: 24062486 Free PMC article.
A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions.
Gunnarsen KS, Høydahl LS, Risnes LF, Dahal-Koirala S, Neumann RS, Bergseng E, Frigstad T, Frick R, du Pré MF, Dalhus B, Lundin KE, Qiao SW, Sollid LM, Sandlie I, Løset GÅ. Gunnarsen KS, et al. Among authors: hoydahl ls. JCI Insight. 2017 Sep 7;2(17):e95193. doi: 10.1172/jci.insight.95193. eCollection 2017 Sep 7. JCI Insight. 2017. PMID: 28878121 Free PMC article.
Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture.
Bjerregaard-Andersen K, Johannesen H, Abdel-Rahman N, Heggelund JE, Hoås HM, Abraha F, Bousquet PA, Høydahl LS, Burschowsky D, Rojas G, Oscarson S, Løset GÅ, Krengel U. Bjerregaard-Andersen K, et al. Among authors: hoydahl ls. Sci Rep. 2018 Jul 18;8(1):10836. doi: 10.1038/s41598-018-28918-5. Sci Rep. 2018. PMID: 30022069 Free PMC article.
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease.
Høydahl LS, Richter L, Frick R, Snir O, Gunnarsen KS, Landsverk OJB, Iversen R, Jeliazkov JR, Gray JJ, Bergseng E, Foss S, Qiao SW, Lundin KEA, Jahnsen J, Jahnsen FL, Sandlie I, Sollid LM, Løset GÅ. Høydahl LS, et al. Gastroenterology. 2019 Apr;156(5):1428-1439.e10. doi: 10.1053/j.gastro.2018.12.013. Epub 2018 Dec 26. Gastroenterology. 2019. PMID: 30593798 Free PMC article.
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