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Combining baloxavir marboxil with standard-of-care neuraminidase inhibitor in patients hospitalised with severe influenza (FLAGSTONE): a randomised, parallel-group, double-blind, placebo-controlled, superiority trial.
Kumar D, Ison MG, Mira JP, Welte T, Hwan Ha J, Hui DS, Zhong N, Saito T, Katugampola L, Collinson N, Williams S, Wildum S, Ackrill A, Clinch B, Lee N. Kumar D, et al. Among authors: katugampola l. Lancet Infect Dis. 2022 May;22(5):718-730. doi: 10.1016/S1473-3099(21)00469-2. Epub 2022 Jan 24. Lancet Infect Dis. 2022. PMID: 35085510 Clinical Trial.
The primary endpoint was time to clinical improvement, defined as time to a NEWS2 of 2 or lower for 24 h or hospital discharge, whichever came first, based on daily assessments over the study duration of 35 days. ...Median time to clinical improvement was 97.5 h (95 …
The primary endpoint was time to clinical improvement, defined as time to a NEWS2 of 2 or lower for 24 h or hospital discharge, which …
Efficacy of HER2-Targeted Intraperitoneal 225Ac α-Pretargeted Radioimmunotherapy for Small-Volume Ovarian Peritoneal Carcinomatosis.
Chung SK, Vargas DB, Chandler CS, Katugampola S, Veach DR, McDevitt MR, Seo SH, Vaughn BA, Rinne SS, Punzalan B, Patel M, Xu H, Guo HF, Zanzonico PB, Monette S, Yang G, Ouerfelli O, Nash GM, Cercek A, Fung EK, Howell RW, Larson SM, Cheal SM, Cheung NV. Chung SK, et al. Among authors: katugampola s. J Nucl Med. 2023 Sep;64(9):1439-1445. doi: 10.2967/jnumed.122.265095. Epub 2023 Jun 22. J Nucl Med. 2023. PMID: 37348919 Free PMC article.
Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome.
Bax HJ, Chauhan J, Stavraka C, Khiabany A, Nakamura M, Pellizzari G, Ilieva KM, Lombardi S, Gould HJ, Corrigan CJ, Till SJ, Katugampola S, Jones PS, Barton C, Winship A, Ghosh S, Montes A, Josephs DH, Spicer JF, Karagiannis SN. Bax HJ, et al. Among authors: katugampola s. Cells. 2020 Jul 7;9(7):1631. doi: 10.3390/cells9071631. Cells. 2020. PMID: 32645919 Free PMC article.
Investigations of the novel checkpoint kinase 1 inhibitor SRA737 in non-small cell lung cancer and colorectal cancer cells of differing tumour protein 53 gene status.
Duabil AJ, Cooper CR, Aldujaily E, Halford SE, Hirschberg S, Katugampola SD, Jones GD. Duabil AJ, et al. Among authors: katugampola sd. Explor Target Antitumor Ther. 2023;4(5):1210-1226. doi: 10.37349/etat.2023.00193. Epub 2023 Dec 21. Explor Target Antitumor Ther. 2023. PMID: 38214010 Free PMC article.
METHODS: NSCLC cell lines H23 [TP53 mutant (MUT)] and A549 [TP53 wild-type (WT)] and CRC cell lines HT29 (TP53 MUT) and HCT116 (TP53 WT) were incubated with differing micromolar concentrations of SRA737 for 24 h and then analysed using alkaline comet and phosphorylated H2A …
METHODS: NSCLC cell lines H23 [TP53 mutant (MUT)] and A549 [TP53 wild-type (WT)] and CRC cell lines HT29 (TP53 MUT) and HCT116 (TP53 WT) wer …
Isolation of bioactive compounds from Helix aspersa nerve tissue and the effect of pQPPLPRYamide on heart, esophagus and central neurons of H. aspersa and rectum of Anodonta woodiana.
Ohtani M, Muneoka Y, Matsushima O, Takao T, Shimonishi Y, White AR, Pedder S, Sharma R, Lennon MA, Katugampola S, Walker RJ. Ohtani M, et al. Among authors: katugampola s. Gen Pharmacol. 1997 Jul;29(1):103-11. doi: 10.1016/s0306-3623(96)00532-0. Gen Pharmacol. 1997. PMID: 9195201
Ha-4, pQPPLPRYamide, was found to excite the heart of H. aspersa, relax the esophagus and both excite (mainly) and inhibit central neurons. ...
Ha-4, pQPPLPRYamide, was found to excite the heart of H. aspersa, relax the esophagus and both excite (mainly) and inhibit central ne …