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Inhibition by 5-(substituted-benzyl)-2,4-diaminopyrimidines of murine tumor (L5178Y) cell cultures sensitive to and resistant to methotrexate. Further evidence for the sensitivity of resistant cells to hydrophobic drugs.
Selassie CD, Li R, Hansch C, Khwaja TA, Dias CB. Selassie CD, et al. Among authors: hansch c. J Med Chem. 1982 May;25(5):518-22. doi: 10.1021/jm00347a007. J Med Chem. 1982. PMID: 7086836
These results are similar to those found for 2,4-diaminotriazines (Selassie, C.D.; Guo, Z. R.; Hansch, C.; Khwaja, T. A.; Pentecost, S. J. Med. ...
These results are similar to those found for 2,4-diaminotriazines (Selassie, C.D.; Guo, Z. R.; Hansch, C.; Khwaja, T. A …
283 results