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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 4
1970 4
1971 8
1972 3
1973 4
1974 9
1975 32
1976 17
1977 22
1978 27
1979 31
1980 39
1981 43
1982 37
1983 56
1984 75
1985 64
1986 85
1987 93
1988 102
1989 107
1990 118
1991 129
1992 150
1993 117
1994 140
1995 123
1996 130
1997 108
1998 109
1999 96
2000 104
2001 111
2002 120
2003 113
2004 124
2005 111
2006 98
2007 108
2008 103
2009 109
2010 111
2011 101
2012 97
2013 262
2014 171
2015 120
2016 101
2017 106
2018 148
2019 144
2020 138
2021 110
2022 102
2023 107
2024 32

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4,651 results

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Page 1
HEPES-buffering of bicarbonate-containing culture medium perturbs lysosomal glucocerebrosidase activity.
van der Lienden MJC, Aten J, Boot RG, van Eijk M, Aerts JMFG, Kuo CL. van der Lienden MJC, et al. J Cell Biochem. 2022 May;123(5):893-905. doi: 10.1002/jcb.30234. Epub 2022 Mar 21. J Cell Biochem. 2022. PMID: 35312102 Free PMC article.
Specific attention was paid to the impact of 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) supplementation to bicarbonate-buffered medium. Here, we report how HEPES-buffered medium markedly influences processing of GCase, its lysosomal degradation, and …
Specific attention was paid to the impact of 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) supplementation to bicarbonat …
Understanding structure activity relationships of Good HEPES lipids for lipid nanoparticle mRNA vaccine applications.
Goldman RL, Vittala Murthy NT, Northen TP, Balakrishnan A, Chivukula S, Danz H, Tibbitts T, Dias A, Vargas J, Cooper D, Gopani H, Beaulieu A, Kalnin KV, Plitnik T, Karmakar S, Dasari R, Landis R, Karve S, DeRosa F. Goldman RL, et al. Biomaterials. 2023 Oct;301:122243. doi: 10.1016/j.biomaterials.2023.122243. Epub 2023 Jul 8. Biomaterials. 2023. PMID: 37480759 Free article.
Herein, we describe a novel family of ionizable lipids synthesized with a piperazine core derived from the HEPES Good buffer. These ionizable lipids have unique asymmetric tails and two dissimilar degradable moieties incorporated within the structure. ...The LNP structure …
Herein, we describe a novel family of ionizable lipids synthesized with a piperazine core derived from the HEPES Good buffer. These i …
HEPES-stabilized encapsulation of Salmonella typhimurium.
Suo Z, Yang X, Avci R, Kellerman L, Pascual DW, Fries M, Steele A. Suo Z, et al. Langmuir. 2007 Jan 30;23(3):1365-74. doi: 10.1021/la0621721. Langmuir. 2007. PMID: 17241060
For bacteria rinsed with HEPES and air-dried, the height images showed only the contour of the capsular material, while the phase and amplitude images presented the detailed structures of the bacterial surface, including the flagella encapsulated inside the capsular EPS. T …
For bacteria rinsed with HEPES and air-dried, the height images showed only the contour of the capsular material, while the phase and …
HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution.
Tol MJ, van der Lienden MJC, Gabriel TL, Hagen JJ, Scheij S, Veenendaal T, Klumperman J, Donker-Koopman WE, Verhoeven AJ, Overkleeft H, Aerts JM, Argmann CA, van Eijk M. Tol MJ, et al. Autophagy. 2018;14(3):437-449. doi: 10.1080/15548627.2017.1419118. Epub 2018 Feb 17. Autophagy. 2018. PMID: 29455584 Free PMC article.
Supplementation of HEPES to cell growth media is sufficient to decouple the MiT/TFE family members-TFEB, TFE3 and MITF-from regulatory mechanisms that control their cytosolic retention. ...In addition, siRNA-mediated MiT/TFE knockdown effectively blunted HEPES-induc …
Supplementation of HEPES to cell growth media is sufficient to decouple the MiT/TFE family members-TFEB, TFE3 and MITF-from regulator …
HEPES inhibits the conversion of prion protein in cell culture.
Delmouly K, Belondrade M, Casanova D, Milhavet O, Lehmann S. Delmouly K, et al. J Gen Virol. 2011 May;92(Pt 5):1244-1250. doi: 10.1099/vir.0.027334-0. Epub 2011 Feb 2. J Gen Virol. 2011. PMID: 21289158
HEPES is a well-known buffering reagent used in cell-culture medium. ...These results could modify the interpretation of cell-culture assays of prion therapeutic agents, as well as of previous cell biology results obtained in the field using HEPES buffers. This inhi
HEPES is a well-known buffering reagent used in cell-culture medium. ...These results could modify the interpretation of cell-culture
A Specific HPLC Method to Determine Residual HEPES in [(68)Ga]Ga-Radiopharmaceuticals: Development and Validation.
Migliari S, Scarlattei M, Baldari G, Silva C, Ruffini L. Migliari S, et al. Molecules. 2022 Jul 13;27(14):4477. doi: 10.3390/molecules27144477. Molecules. 2022. PMID: 35889351 Free PMC article.
Results: In the assessed samples, HEPES could not be detected by the TLC method that was described in Ph. ...Conclusions: The TLC method that is described in Ph. Eur. to assess residual HEPES in [68Ga]-based radiopharmaceuticals may not be sufficiently sensitive and …
Results: In the assessed samples, HEPES could not be detected by the TLC method that was described in Ph. ...Conclusions: The TLC met …
The gradient-like separation and reduced running time with Tris-Tricine-HEPES buffer for SDS-PAGE.
Dumut DC, Garić D, Centorame A, Radzioch D. Dumut DC, et al. Anal Biochem. 2022 Sep 15;653:114789. doi: 10.1016/j.ab.2022.114789. Epub 2022 Jun 20. Anal Biochem. 2022. PMID: 35738440
Here we describe a protocol for gradient-like simultaneous separation of small (<10 kDa) and large (>400 kDa) proteins in a single percentage polyacrylamide Tris-Acetate gel using a novel running buffer composed of Tris, Tricine and HEPES....
Here we describe a protocol for gradient-like simultaneous separation of small (<10 kDa) and large (>400 kDa) proteins in a single per …
Interaction of HEPES buffer with glass-ceramic scaffold: Can HEPES replace TRIS in SBF?
Rohanová D, Horkavcová D, Paidere L, Boccaccini AR, Bozděchová P, Bezdička P. Rohanová D, et al. J Biomed Mater Res B Appl Biomater. 2018 Jan;106(1):143-152. doi: 10.1002/jbm.b.33818. Epub 2016 Nov 27. J Biomed Mater Res B Appl Biomater. 2018. PMID: 27889932
We compared its suitability in two media: SBF with HEPES and demineralized water with HEPES. The tested scaffold (45S5 bioactive glass-based) was exposed to the media under a static-dynamic arrangement (solutions were replaced on a daily basis) for 15 days. ...The I …
We compared its suitability in two media: SBF with HEPES and demineralized water with HEPES. The tested scaffold (45S5 bioacti …
HEPES buffer perfusate alters rabbit lung endothelial permeability.
Douglas GC, Swanson JA, Kern DF. Douglas GC, et al. J Appl Physiol (1985). 1993 Sep;75(3):1423-5. doi: 10.1152/jappl.1993.75.3.1423. J Appl Physiol (1985). 1993. PMID: 8226560
Cationic albumin permeability increased with 12 mM HEPES (8.7phosphate-->30(12) mM HEPES x ml.min-1.g dry lung-1 x 10(-2)) as did the anionic albumin PS (2.7phosphate-->3.52(12) mM HEPES). The cationic PS returned to baseline (8.1(60) mM HEPES) a …
Cationic albumin permeability increased with 12 mM HEPES (8.7phosphate-->30(12) mM HEPES x ml.min-1.g dry lung-1 x 10(-2)) …
HEPES inhibits contractile responses of canine basilar artery.
Kane J, Macdonald RL, Zhang J, Sima B. Kane J, et al. Neurol Res. 1997 Oct;19(5):527-33. doi: 10.1080/01616412.1997.11740852. Neurol Res. 1997. PMID: 9329031
N-2-hydroxyethylpiperazine-N'-2-ethanesulphonic acid (HEPES) is a commonly-used buffer. This study determined the effect of HEPES on contractility of the dog basilar artery and tested the hypothesis that HEPES inhibits vasoconstriction of isolated arterial se …
N-2-hydroxyethylpiperazine-N'-2-ethanesulphonic acid (HEPES) is a commonly-used buffer. This study determined the effect of HEPES
4,651 results