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A replication-linked mutational gradient drives somatic mutation accumulation and influences germline polymorphisms and genome composition in mitochondrial DNA.
Sanchez-Contreras M, Sweetwyne MT, Kohrn BF, Tsantilas KA, Hipp MJ, Schmidt EK, Fredrickson J, Whitson JA, Campbell MD, Rabinovitch PS, Marcinek DJ, Kennedy SR. Sanchez-Contreras M, et al. Nucleic Acids Res. 2021 Nov 8;49(19):11103-11118. doi: 10.1093/nar/gkab901. Nucleic Acids Res. 2021. PMID: 34614167 Free PMC article.