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Year Number of Results
2014 1
2015 1
2017 4
2018 5
2019 9
2020 5
2021 1
2022 4
2023 1
2024 0

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Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT2C Receptor and Dual 5-HT2C/5-HT2A Receptor Modulators.
Chen J, Garcia EJ, Merritt CR, Zamora JC, Bolinger AA, Pazdrak K, Stafford SJ, Mifflin RC, Wold EA, Wild CT, Chen H, Anastasio NC, Cunningham KA, Zhou J. Chen J, et al. J Med Chem. 2023 Jul 27;66(14):9992-10009. doi: 10.1021/acs.jmedchem.3c00908. Epub 2023 Jul 18. J Med Chem. 2023. PMID: 37462530 Free PMC article.
Measuring Nonapoptotic Caspase Activity with a Transgenic Reporter in Mice.
Nicholls PJ, Pack TF, Urs NM, Kumar S, Zhou Y, Ichim G, Ginzel JD, Turu G, Calabrese E, Roberts WL, Fan P, Ostapchenko VG, Guzman Lenis MS, Beraldo F, Hatina J, Prado VF, Prado MAM, Spasojevic I, Snyder JC, Dzirasa K, Johnson GA, Caron MG. Nicholls PJ, et al. eNeuro. 2022 Oct 4;9(5):ENEURO.0147-21.2022. doi: 10.1523/ENEURO.0147-21.2022. Print 2022 Sep-Oct. eNeuro. 2022. PMID: 36635920 Free PMC article.
σ2R/TMEM97 in retinal ganglion cell degeneration.
Wang H, Peng Z, Li Y, Sahn JJ, Hodges TR, Chou TH, Liu Q, Zhou X, Jiao S, Porciatti V, Liebl DJ, Martin SF, Wen R. Wang H, et al. Sci Rep. 2022 Dec 1;12(1):20753. doi: 10.1038/s41598-022-24537-3. Sci Rep. 2022. PMID: 36456686 Free PMC article.
Development and use of a high-throughput screen to identify novel modulators of the corticotropin releasing factor binding protein.
Haass-Koffler CL, Francis TC, Gandhi P, Patel R, Naemuddin M, Nielsen CK, Bartlett SE, Bonci A, Vasile S, Hood BL, Suyama E, Hedrick MP, Smith LH, Limpert AS, Roberto M, Cosford NDP, Sheffler DJ. Haass-Koffler CL, et al. SLAS Discov. 2022 Dec;27(8):448-459. doi: 10.1016/j.slasd.2022.09.005. Epub 2022 Oct 7. SLAS Discov. 2022. PMID: 36210051 Free PMC article.
Evaluation of Urea-Based Inhibitors of the Dopamine Transporter Using the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis.
Ashraf-Uz-Zaman M, Ji G, Tidwell D, Yin L, Thakolwiboon S, Pan J, Junell R, Griffin Z, Shahi S, Barthels D, Sajib MS, Trippier PC, Mikelis CM, Das H, Avila M, Neugebauer V, German NA. Ashraf-Uz-Zaman M, et al. ACS Chem Neurosci. 2022 Jan 19;13(2):217-228. doi: 10.1021/acschemneuro.1c00647. Epub 2022 Jan 3. ACS Chem Neurosci. 2022. PMID: 34978174 Free PMC article.
Design, Synthesis, and Characterization of Benzimidazole Derivatives as Positron Emission Tomography Imaging Ligands for Metabotropic Glutamate Receptor 2.
Yuan G, Qu X, Zheng B, Neelamegam R, Afshar S, Iyengar S, Pan C, Wang J, Kang HJ, Ondrechen MJ, Poutiainen P, El Fakhri G, Zhang Z, Brownell AL. Yuan G, et al. J Med Chem. 2020 Oct 22;63(20):12060-12072. doi: 10.1021/acs.jmedchem.0c01394. Epub 2020 Oct 7. J Med Chem. 2020. PMID: 32981322 Free PMC article.
29 results