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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 8
1981 13
1982 14
1983 23
1984 7
1985 17
1986 16
1987 22
1988 13
1989 15
1990 14
1991 13
1992 19
1993 15
1994 17
1995 16
1996 12
1997 7
1998 12
1999 12
2000 13
2001 9
2002 22
2003 13
2004 14
2005 7
2006 10
2007 13
2008 12
2009 10
2010 7
2011 1
2012 8
2013 6
2014 2
2015 4
2019 1
2020 0
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Article type
Publication date

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428 results
Results by year
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Page 1
A century of cholesterol and coronaries: from plaques to genes to statins.
Goldstein JL, Brown MS. Goldstein JL, et al. Cell. 2015 Mar 26;161(1):161-172. doi: 10.1016/j.cell.2015.01.036. Cell. 2015. PMID: 25815993 Free PMC article. Review.
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver.
Horton JD, Goldstein JL, Brown MS. Horton JD, et al. J Clin Invest. 2002 May;109(9):1125-31. doi: 10.1172/JCI15593. J Clin Invest. 2002. PMID: 11994399 Free PMC article. Review. No abstract available.
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.
Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH. Cohen JC, et al. N Engl J Med. 2006 Mar 23;354(12):1264-72. doi: 10.1056/NEJMoa054013. N Engl J Med. 2006. PMID: 16554528 Free article.
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease.
Romeo S, Kozlitina J, Xing C, Pertsemlidis A, Cox D, Pennacchio LA, Boerwinkle E, Cohen JC, Hobbs HH. Romeo S, et al. Nat Genet. 2008 Dec;40(12):1461-5. doi: 10.1038/ng.257. Epub 2008 Sep 25. Nat Genet. 2008. PMID: 18820647 Free PMC article.
Molecular genetics of the LDL receptor gene in familial hypercholesterolemia.
Hobbs HH, Brown MS, Goldstein JL. Hobbs HH, et al. Hum Mutat. 1992;1(6):445-66. doi: 10.1002/humu.1380010602. Hum Mutat. 1992. PMID: 1301956 Review.
Molecular mediators of hepatic steatosis and liver injury.
Browning JD, Horton JD. Browning JD, et al. J Clin Invest. 2004 Jul;114(2):147-52. doi: 10.1172/JCI22422. J Clin Invest. 2004. PMID: 15254578 Free PMC article. Review.
Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity.
Browning JD, Szczepaniak LS, Dobbins R, Nuremberg P, Horton JD, Cohen JC, Grundy SM, Hobbs HH. Browning JD, et al. Hepatology. 2004 Dec;40(6):1387-95. doi: 10.1002/hep.20466. Hepatology. 2004. PMID: 15565570
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.
Ye J, Rawson RB, Komuro R, Chen X, Davé UP, Prywes R, Brown MS, Goldstein JL. Ye J, et al. Mol Cell. 2000 Dec;6(6):1355-64. doi: 10.1016/s1097-2765(00)00133-7. Mol Cell. 2000. PMID: 11163209 Free article.
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates.
Frank-Kamenetsky M, Grefhorst A, Anderson NN, Racie TS, Bramlage B, Akinc A, Butler D, Charisse K, Dorkin R, Fan Y, Gamba-Vitalo C, Hadwiger P, Jayaraman M, John M, Jayaprakash KN, Maier M, Nechev L, Rajeev KG, Read T, Röhl I, Soutschek J, Tan P, Wong J, Wang G, Zimmermann T, de Fougerolles A, Vornlocher HP, Langer R, Anderson DG, Manoharan M, Koteliansky V, Horton JD, Fitzgerald K. Frank-Kamenetsky M, et al. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11915-20. doi: 10.1073/pnas.0805434105. Epub 2008 Aug 11. Proc Natl Acad Sci U S A. 2008. PMID: 18695239 Free PMC article.
Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER.
Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, Goldstein JL, Brown MS. Yang T, et al. Cell. 2002 Aug 23;110(4):489-500. doi: 10.1016/s0092-8674(02)00872-3. Cell. 2002. PMID: 12202038 Free article.
428 results
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