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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1976 28
1977 64
1978 45
1979 52
1980 36
1981 30
1982 53
1983 90
1984 70
1985 72
1986 53
1987 65
1988 80
1989 50
1990 60
1991 44
1992 53
1993 44
1994 50
1995 56
1996 54
1997 56
1998 74
1999 38
2000 51
2001 47
2002 60
2003 42
2004 55
2005 57
2006 74
2007 65
2008 71
2009 94
2010 75
2011 85
2012 102
2013 115
2014 100
2015 92
2016 100
2017 95
2018 95
2019 103
2020 84
2021 109
2022 119
2023 80
2024 78
2025 78
2026 41

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3,194 results

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Page 1
Ankylosing spondylitis: From pathogenesis to therapy.
Wei Y, Zhang S, Shao F, Sun Y. Wei Y, et al. Int Immunopharmacol. 2025 Jan 3;145:113709. doi: 10.1016/j.intimp.2024.113709. Epub 2024 Dec 6. Int Immunopharmacol. 2025. PMID: 39644789 Review.
Ankylosing spondylitis (AS) is an autoimmune rheumatic disease that primarily affects the axial joints, with its etiology complex and still not fully understood. The unknown pathogenesis of AS limits the development of treatment strategies, so keeping up-to-date wit …
Ankylosing spondylitis (AS) is an autoimmune rheumatic disease that primarily affects the axial joints, with its etiology comp …
A short review on deciphering Vyadhikshamatva: insights from HLA-B27-ankylosing spondylitis relation.
P AT, Deogade MS, Nesari TM, Ramachandran A. P AT, et al. J Complement Integr Med. 2024 May 6;21(2):264-267. doi: 10.1515/jcim-2024-0083. eCollection 2024 Jun 1. J Complement Integr Med. 2024. PMID: 38702944 Review.
OBJECTIVES: Various aspects of the concept of Vyadhikshamatva have been thoroughly explored, highlighting its profound significance in resisting disease manifestation, particularly in the context of Ankylosing spondylitis. Investigated the relationship between HL …
OBJECTIVES: Various aspects of the concept of Vyadhikshamatva have been thoroughly explored, highlighting its profound significance in resis …
Role of HLA-B27 in the pathogenesis of ankylosing spondylitis (Review).
Chen B, Li J, He C, Li D, Tong W, Zou Y, Xu W. Chen B, et al. Mol Med Rep. 2017 Apr;15(4):1943-1951. doi: 10.3892/mmr.2017.6248. Epub 2017 Feb 24. Mol Med Rep. 2017. PMID: 28259985 Free PMC article. Review.
However, human leukocyte antigen (HLA)-B27 has been suggested to be important in the pathogenesis of AS, contributing to ~20.1% of AS heritability. ...The aim of the present review is to provide an update of the current research into the pathogenesis of AS, a …
However, human leukocyte antigen (HLA)-B27 has been suggested to be important in the pathogenesis of AS, contributing t …
The association of HLA-B27 and Klebsiella pneumoniae in ankylosing spondylitis: A systematic review.
Zhang L, Zhang YJ, Chen J, Huang XL, Fang GS, Yang LJ, Duan Y, Wang J. Zhang L, et al. Microb Pathog. 2018 Apr;117:49-54. doi: 10.1016/j.micpath.2018.02.020. Epub 2018 Feb 10. Microb Pathog. 2018. PMID: 29438717
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis of unknown origin. Its autoimmune origin has been suggested but never proven. Several reports have implicated K. pneumoniae as a triggering or perpetuating factor in AS; and the HLA-B27 …
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis of unknown origin. Its autoimmune origin has been suggested bu …
HLA-B27 and ankylosing spondylitis geographic distribution as the result of a genetic selection induced by malaria endemic? A review supporting the hypothesis.
Mathieu A, Cauli A, Fiorillo MT, Sorrentino R. Mathieu A, et al. Autoimmun Rev. 2008 May;7(5):398-403. doi: 10.1016/j.autrev.2008.03.013. Epub 2008 Apr 9. Autoimmun Rev. 2008. PMID: 18486928 Review.
The geographic distribution of HLA-B27 shows a latitude-related gradient inverse to that of malaria endemic. An apparent exception occurs in New Guinea, a region where malaria is present, but where HLA-B27 frequency shows, however, an orographic gradie …
The geographic distribution of HLA-B27 shows a latitude-related gradient inverse to that of malaria endemic. An apparent excep …
Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility in HLA-B27 positive population: a Meta-analysis and bioinformatics analysis.
Bai Y, Zhao N, Sun H, Yin L, Chen J, Hu N. Bai Y, et al. Nucleosides Nucleotides Nucleic Acids. 2022;41(4):407-418. doi: 10.1080/15257770.2022.2036344. Epub 2022 Feb 9. Nucleosides Nucleotides Nucleic Acids. 2022. PMID: 35139766
Human leukocyte antigen (HLA)-B27 confers a key role in ankylosing spondylitis (AS) susceptibility. Endoplasmic reticulum aminopeptidase 1 (ERAP1) polymorphisms are associated with AS susceptibility in common population. ...Rs2287987 in ERAP1 ma …
Human leukocyte antigen (HLA)-B27 confers a key role in ankylosing spondylitis (AS) susceptibility. Endop …
Guilt by association: HLA-B27 and ankylosing spondylitis.
Benjamin R, Parham P. Benjamin R, et al. Immunol Today. 1990 Apr;11(4):137-42. doi: 10.1016/0167-5699(90)90051-a. Immunol Today. 1990. PMID: 2187471 Review.
The remarkable association between HLA-B27 and ankylosing spondylitis (AS) remains an enigma. While previous reviews have discussed the controversies surrounding the involvement of bacteria in the etiology of this disease and the sequence variability b …
The remarkable association between HLA-B27 and ankylosing spondylitis (AS) remains an enigma. While previous rev …
HLA B27 in Ankylosing Spondylitis: Differences in Frequency and Relative Risk in American Blacks and Caucasians.
Khan MA, Braun WE, Kushner I, Grecek DE, Muir WA, Steinberg AG. Khan MA, et al. J Rheumatol. 2023 Jan;50(1):39-43. J Rheumatol. 2023. PMID: 36587954
Twenty-eight HLA alleles of the A and B loci were determined in 23 American Blacks and 50 Caucasians with primary ankylosing spondylitis (AS). The prevalence of HLA B27 was significantly increased in American Black patients (48 per cent) vs Blac …
Twenty-eight HLA alleles of the A and B loci were determined in 23 American Blacks and 50 Caucasians with primary ankylosing …
HLA-B27-associated gut microbiota and amino acid perturbations promote ankylosing spondylitis through M1 macrophage activation.
Huang T, Yang H, Zhang L, Wang X, Chen Y, Dai H, Hashimoto K, Luo Y, Pu Y, Liu Y. Huang T, et al. Gut Microbes. 2026 Dec 31;18(1):2630561. doi: 10.1080/19490976.2026.2630561. Epub 2026 Feb 16. Gut Microbes. 2026. PMID: 41698880 Free PMC article.
Ankylosing spondylitis (AS) is strongly associated with the human leukocyte antigen B27 (HLA-B27), yet how this genetic risk factor interacts with the gut microbiome remains unclear. We integrated fecal gut microbiota analysis, untargeted …
Ankylosing spondylitis (AS) is strongly associated with the human leukocyte antigen B27 (HLA-B27), …
3,194 results