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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1990 10
1991 13
1992 9
1993 19
1994 19
1995 24
1996 35
1997 45
1998 33
1999 105
2000 70
2001 51
2002 52
2003 91
2004 63
2005 89
2006 106
2007 145
2008 115
2009 139
2010 124
2011 154
2012 152
2013 165
2014 164
2015 147
2016 146
2017 129
2018 125
2019 112
2020 132
2021 135
2022 86
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2,679 results
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Page 1
HLA-G: A New Immune Checkpoint in Cancer?
Krijgsman D, Roelands J, Hendrickx W, Bedognetti D, Kuppen PJK. Krijgsman D, et al. Int J Mol Sci. 2020 Jun 25;21(12):4528. doi: 10.3390/ijms21124528. Int J Mol Sci. 2020. PMID: 32630545 Free PMC article. Review.
Many studies have claimed HLA-G as a new immune checkpoint in cancer. Therefore, HLA-G and its receptors might be targets for immune checkpoint blockade in cancer immunotherapy. ...These studies should focus on tumor expression patterns of the seven di …
Many studies have claimed HLA-G as a new immune checkpoint in cancer. Therefore, HLA-G and its receptors might b …
HLA-G: At the Interface of Maternal-Fetal Tolerance.
Ferreira LMR, Meissner TB, Tilburgs T, Strominger JL. Ferreira LMR, et al. Trends Immunol. 2017 Apr;38(4):272-286. doi: 10.1016/j.it.2017.01.009. Epub 2017 Mar 6. Trends Immunol. 2017. PMID: 28279591 Review.
Several mechanisms were initially proposed by Peter Medawar half a century ago to explain this apparent violation of the laws of transplantation. Then, three decades ago, an unusual human leukocyte antigen (HLA) molecule was identified: HLA-G. Uniquely expres …
Several mechanisms were initially proposed by Peter Medawar half a century ago to explain this apparent violation of the laws of transplanta …
HLA-G: An Immune Checkpoint Molecule.
Carosella ED, Rouas-Freiss N, Tronik-Le Roux D, Moreau P, LeMaoult J. Carosella ED, et al. Adv Immunol. 2015;127:33-144. doi: 10.1016/bs.ai.2015.04.001. Epub 2015 May 27. Adv Immunol. 2015. PMID: 26073983 Review.
The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions …
The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, memb …
HLA-G/ILTs Targeted Solid Cancer Immunotherapy: Opportunities and Challenges.
Lin A, Yan WH. Lin A, et al. Front Immunol. 2021 Jun 30;12:698677. doi: 10.3389/fimmu.2021.698677. eCollection 2021. Front Immunol. 2021. PMID: 34276691 Free PMC article. Review.
HLA-G/ILT-2/-4 (HLA-G/ILTs) signaling can drive comprehensive immune suppression, promote tumor growth and disease progression. Though clinical benefits could be expected with application of HLA-G antibodies to blockade the HLA-
HLA-G/ILT-2/-4 (HLA-G/ILTs) signaling can drive comprehensive immune suppression, promote tumor growth and disea
HLA-G expression in melanomas.
Marletta S, Girolami I, Munari E, Pantanowitz L, Bernasconi R, Torresani E, Brunelli M, Eccher A. Marletta S, et al. Int Rev Immunol. 2021;40(5):330-343. doi: 10.1080/08830185.2020.1869732. Epub 2021 Jan 11. Int Rev Immunol. 2021. PMID: 33426980 Review.
OBJECTIVE: Human leukocyte antigen G (HLA-G) is a non-classical HLA class I molecule involved in inducing tolerance at the feto-maternal interface and in escape of immune response by tumor cells. ...Evidence further suggests that HLA-G is …
OBJECTIVE: Human leukocyte antigen G (HLA-G) is a non-classical HLA class I molecule involved in inducing tolera …
HLA-G Neo-Expression on Tumors.
Loustau M, Anna F, Dréan R, Lecomte M, Langlade-Demoyen P, Caumartin J. Loustau M, et al. Front Immunol. 2020 Aug 14;11:1685. doi: 10.3389/fimmu.2020.01685. eCollection 2020. Front Immunol. 2020. PMID: 32922387 Free PMC article. Review.
Consequently, HLA-G appears to be an excellent molecular target for immunotherapy. ...Here, we summarize the current knowledge about HLA-G neo-expression and implication in various tumor types, pointing out the need for the development of new tools to …
Consequently, HLA-G appears to be an excellent molecular target for immunotherapy. ...Here, we summarize the current knowledge …
HLA-G: Function, polymorphisms and pathology.
Arnaiz-Villena A, Juarez I, Suarez-Trujillo F, López-Nares A, Vaquero C, Palacio-Gruber J, Martin-Villa JM. Arnaiz-Villena A, et al. Int J Immunogenet. 2021 Apr;48(2):172-192. doi: 10.1111/iji.12513. Epub 2020 Oct 1. Int J Immunogenet. 2021. PMID: 33001562 Review.
HLA-G immune modulatory genes and molecules are presently being studied by a widespread number of research groups. ...On the other hand, we question whether performing mainly studies on HLA-G and disease associations is going to give a clear answer in
HLA-G immune modulatory genes and molecules are presently being studied by a widespread number of research groups. ...On the o
HLA-G: An Important Mediator of Maternal-Fetal Immune-Tolerance.
Zhuang B, Shang J, Yao Y. Zhuang B, et al. Front Immunol. 2021 Oct 29;12:744324. doi: 10.3389/fimmu.2021.744324. eCollection 2021. Front Immunol. 2021. PMID: 34777357 Free PMC article. Review.
HLA-G is widely regarded as the pivotal protective factor for successful pregnancies. In the past 20 years, researches associated with HLA-G have been continually published. Indeed, HLA-G plays a mysterious role in the mechanism of matern
HLA-G is widely regarded as the pivotal protective factor for successful pregnancies. In the past 20 years, researches associa
HLA-G/sHLA-G and HLA-G-Bearing Extracellular Vesicles in Cancers: Potential Role as Biomarkers.
Li P, Wang N, Zhang Y, Wang C, Du L. Li P, et al. Front Immunol. 2021 Nov 11;12:791535. doi: 10.3389/fimmu.2021.791535. eCollection 2021. Front Immunol. 2021. PMID: 34868081 Free PMC article. Review.
However, because HLA-G itself has up to seven different subtypes, and for some subtypes, detected antibodies are few or absent, it is hard to evaluate the actual expression of HLA-G in tumors. In the present work, we described (a) the structure and thr …
However, because HLA-G itself has up to seven different subtypes, and for some subtypes, detected antibodies are few or absent …
HLA-G Genotype/Expression/Disease Association Studies: Success, Hurdles, and Perspectives.
Amodio G, Gregori S. Amodio G, et al. Front Immunol. 2020 Jul 8;11:1178. doi: 10.3389/fimmu.2020.01178. eCollection 2020. Front Immunol. 2020. PMID: 32733439 Free PMC article. Review.
The non-classical HLA-G is a well-known immune-modulatory molecule. In physiological condition, HLA-G surface expression is restricted to the maternal-fetal interface and to immune-privileged adult tissues, whereas soluble forms of HLA-G
The non-classical HLA-G is a well-known immune-modulatory molecule. In physiological condition, HLA-G surface ex …
2,679 results