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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1996 2
1999 2
2000 1
2001 1
2002 1
2003 4
2005 1
2007 1
2008 1
2009 1
2012 1
2013 1
2018 1
2019 1
2020 1
2021 3
2022 1
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23 results
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HCG18 Participates in Vascular Invasion of Hepatocellular Carcinoma by Regulating Macrophages and Tumor Stem Cells.
Zhang L, Wang Z, Li M, Sun P, Bai T, Wang W, Bai H, Gou J, Wang Z. Zhang L, et al. Front Cell Dev Biol. 2021 Aug 30;9:707073. doi: 10.3389/fcell.2021.707073. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34527669 Free PMC article.
Cluster analysis based on patient prognosis suggested that regulating phenotypic transformation of macrophages could be an effective intervention for treating HCC. At the same time, higher expression of HCG18, HMGA1, ILF2, and YBX1 was associated with a higher stem …
Cluster analysis based on patient prognosis suggested that regulating phenotypic transformation of macrophages could be an effective …
Insights into pharmacological mechanisms of polydatin in targeting risk factors-mediated atherosclerosis.
Ahmad P, Alvi SS, Iqbal D, Khan MS. Ahmad P, et al. Life Sci. 2020 Aug 1;254:117756. doi: 10.1016/j.lfs.2020.117756. Epub 2020 May 7. Life Sci. 2020. PMID: 32389832 Review.
The initial part of this report specifically explains distinct sequential mechanisms underlying the initiation and development of atherosclerotic plaques and later part deals with the pharmacological efficacy of PD in the management of major cardiac event i.e. atherosclerotic car …
The initial part of this report specifically explains distinct sequential mechanisms underlying the initiation and development of atheroscle …
HMGA1B/2 transcriptionally activated-POU1F1 facilitates gastric carcinoma metastasis via CXCL12/CXCR4 axis-mediated macrophage polarization.
Tang C, Lei X, Xiong L, Hu Z, Tang B. Tang C, et al. Cell Death Dis. 2021 Apr 29;12(5):422. doi: 10.1038/s41419-021-03703-x. Cell Death Dis. 2021. PMID: 33927188 Free PMC article.
Tumor-associated macrophages (TAMs) in the tumor microenvironment contribute to poor prognosis in gastric cancer (GC). ...POU1F1 also promoted GC metastasis in lung by modulating macrophage polarization through CXCL12/CXCR4 axis in vivo. HMGA1B/2-upregulated …
Tumor-associated macrophages (TAMs) in the tumor microenvironment contribute to poor prognosis in gastric cancer (GC). ...POU1F1 also …
Meta-analysis identifying epithelial-derived transcriptomes predicts poor clinical outcome and immune infiltrations in ovarian cancer.
Li DF, Tulahong A, Uddin MN, Zhao H, Zhang H. Li DF, et al. Math Biosci Eng. 2021 Jul 30;18(5):6527-6551. doi: 10.3934/mbe.2021324. Math Biosci Eng. 2021. PMID: 34517544 Free article.
We identified 21 (such as E2F4, FOXM1, TFDP1, E2F1, and SIN3A) and 11 (such as JUN, DDX4, FOSL1, NOC2L, and HMGA1) master transcriptional regulators (MTRs) that are interacted with upregulated and the downregulated genes in ovarian tumor epithelium, respectively. ...Moreov …
We identified 21 (such as E2F4, FOXM1, TFDP1, E2F1, and SIN3A) and 11 (such as JUN, DDX4, FOSL1, NOC2L, and HMGA1) master transcripti …
Integrative analysis reveals key mRNAs and lncRNAs in monocytes of osteoporotic patients.
Li L, Wang XQ, Liu XT, Guo R, Zhang RD. Li L, et al. Math Biosci Eng. 2019 Jun 27;16(5):5947-5971. doi: 10.3934/mbe.2019298. Math Biosci Eng. 2019. PMID: 31499747 Free article.
In addition, we also highlighted one lncRNA, RP11-498C9.17, was highly correlated with epigenetic regulators, such as HDAC4, MORF4L1, HMGA1 and DND1, indicating that the lncRNA RP11-498C9.17 may also be an epigenetic regulator. ...
In addition, we also highlighted one lncRNA, RP11-498C9.17, was highly correlated with epigenetic regulators, such as HDAC4, MORF4L1, HMG
Frontline Science: Targeted expression of a dominant-negative high mobility group A1 transgene improves outcome in sepsis.
Baron RM, Kwon MY, Castano AP, Ghanta S, Riascos-Bernal DF, Lopez-Guzman S, Macias AA, Ith B, Schissel SL, Lederer JA, Reeves R, Yet SF, Layne MD, Liu X, Perrella MA. Baron RM, et al. J Leukoc Biol. 2018 Oct;104(4):677-689. doi: 10.1002/JLB.4HI0817-333RR. Epub 2018 Jul 5. J Leukoc Biol. 2018. PMID: 29975792 Free PMC article.
High mobility group (HMG) proteins are a family of architectural transcription factors, with HMGA1 playing a role in the regulation of genes involved in promoting systemic inflammatory responses. We speculated that blocking HMGA1-mediated pathways might impro …
High mobility group (HMG) proteins are a family of architectural transcription factors, with HMGA1 playing a role in the regul …
High-Mobility Group AT-Hook 1 Served as a Prognosis Biomarker and Associated with Immune Infiltrate in Hepatocellular Carcinoma.
Wei YG, Yang CK, Wei ZL, Liao XW, He YF, Zhou X, Huang HS, Lan CL, Han CY, Peng T. Wei YG, et al. Int J Gen Med. 2022 Jan 14;15:609-621. doi: 10.2147/IJGM.S344858. eCollection 2022. Int J Gen Med. 2022. PMID: 35058711 Free PMC article.
Notably, HMGA1 may be associated with TP53 mutational carcinogenesis. Moreover, increased HMGA1 expression may lead to an increase in immune infiltration and a decrease in tumor purity in HCC. CIBERSORT analysis elucidated that the amount of B cell naive, B cell mem …
Notably, HMGA1 may be associated with TP53 mutational carcinogenesis. Moreover, increased HMGA1 expression may lead to an incr …
Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation.
Battista S, Pentimalli F, Baldassarre G, Fedele M, Fidanza V, Croce CM, Fusco A. Battista S, et al. FASEB J. 2003 Aug;17(11):1496-8. doi: 10.1096/fj.02-0977fje. Epub 2003 Jun 17. FASEB J. 2003. PMID: 12824305
To assess their role in development, we studied the in vitro differentiation of embryonic stem (ES) cells that bear one or both disrupted Hmga1 alleles. Here, we report that Hmga1 null ES cells generate fewer T-cell precursors than do wild-type ES cells. ...Re-expre …
To assess their role in development, we studied the in vitro differentiation of embryonic stem (ES) cells that bear one or both disrupted …
Netropsin improves survival from endotoxaemia by disrupting HMGA1 binding to the NOS2 promoter.
Grant MA, Baron RM, Macias AA, Layne MD, Perrella MA, Rigby AC. Grant MA, et al. Biochem J. 2009 Feb 15;418(1):103-12. doi: 10.1042/BJ20081427. Biochem J. 2009. PMID: 18937643 Free PMC article.
Netropsin significantly attenuated NOS2 promoter activity in macrophage transient transfection studies and the AT-rich HMGA1 DNA-binding site was critical for this effect. ...Chemical shift perturbation analysis identified that netropsin effectively competes both …
Netropsin significantly attenuated NOS2 promoter activity in macrophage transient transfection studies and the AT-rich HMGA1 D …
23 results