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Plasma and cellular adriamycin concentrations in patients with myeloma treated with ninety-six-hour continuous infusion.
Speth PA, Linssen PC, Holdrinet RS, Haanen C. Speth PA, et al. Among authors: haanen c. Clin Pharmacol Ther. 1987 Jun;41(6):661-5. doi: 10.1038/clpt.1987.92. Clin Pharmacol Ther. 1987. PMID: 3581649
In vivo cellular adriamycin concentrations related to growth inhibition of normal and leukemic human bone marrow cells.
Speth PA, Raijmakers RA, Boezeman JB, Linssen PC, de Witte TJ, Wessels HM, Haanen C. Speth PA, et al. Among authors: haanen c. Eur J Cancer Clin Oncol. 1988 Apr;24(4):667-74. doi: 10.1016/0277-5379(88)90297-0. Eur J Cancer Clin Oncol. 1988. PMID: 3383969
Plasma and human leukemic cell pharmacokinetics of oral and intravenous 4-demethoxydaunomycin.
Speth PA, van de Loo FA, Linssen PC, Wessels HM, Haanen C. Speth PA, et al. Among authors: haanen c. Clin Pharmacol Ther. 1986 Dec;40(6):643-9. doi: 10.1038/clpt.1986.239. Clin Pharmacol Ther. 1986. PMID: 3465490
Cellular and plasma pharmacokinetics of weekly 20-mg 4'-epi-adriamycin bolus injection in patients with advanced breast carcinoma.
Speth PA, Linssen PC, Beex LV, Boezeman JB, Haanen C. Speth PA, et al. Among authors: haanen c. Cancer Chemother Pharmacol. 1986;18(1):78-82. doi: 10.1007/BF00253070. Cancer Chemother Pharmacol. 1986. PMID: 3463436
Cellular and plasma adriamycin concentrations in long-term infusion therapy of leukemia patients.
Speth PA, Linssen PC, Boezeman JB, Wessels HM, Haanen C. Speth PA, et al. Among authors: haanen c. Cancer Chemother Pharmacol. 1987;20(4):305-10. doi: 10.1007/BF00262581. Cancer Chemother Pharmacol. 1987. PMID: 3480081
Leukemic cell and plasma daunomycin concentrations after bolus injection and 72 h infusion.
Speth PA, Linssen PC, Boezeman JB, Wessels HM, Haanen C. Speth PA, et al. Among authors: haanen c. Cancer Chemother Pharmacol. 1987;20(4):311-5. doi: 10.1007/BF00262582. Cancer Chemother Pharmacol. 1987. PMID: 3690804
Infusion-rate independent cellular adriamycin concentrations and cytotoxicity to human bone marrow clonogenic cells (CFU-GM).
Raijmakers R, Speth P, de Witte T, Linssen P, Wessels J, Haanen C. Raijmakers R, et al. Among authors: haanen c. Br J Cancer. 1987 Aug;56(2):123-6. doi: 10.1038/bjc.1987.168. Br J Cancer. 1987. PMID: 3663464 Free PMC article.
Pharmacokinetics of cytosine arabinoside in acute myeloid leukemia.
van Prooijen R, van der Kleijn E, Haanen C. van Prooijen R, et al. Among authors: haanen c. Clin Pharmacol Ther. 1977 Jun;21(6):744-50. doi: 10.1002/cpt1977216744. Clin Pharmacol Ther. 1977. PMID: 266428
In vivo and in vitro pharmacokinetic differences between four structurally closely related anthracyclines in hematopoietic cell subtypes in humans.
Speth PA, Linssen PC, Termond EF, Boezeman JB, Wessels HM, Haanen C. Speth PA, et al. Among authors: haanen c. Drug Metab Dispos. 1989 Jan-Feb;17(1):98-105. Drug Metab Dispos. 1989. PMID: 2566478
Quantitation of anthracyclines in human hematopoietic cell subpopulations by flow cytometry correlated with high pressure liquid chromatography.
Speth PA, Linssen PC, Boezeman JB, Wessels HM, Haanen C. Speth PA, et al. Among authors: haanen c. Cytometry. 1985 Mar;6(2):143-50. doi: 10.1002/cyto.990060210. Cytometry. 1985. PMID: 3856510
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