Haataja L - Search Results

1

Autophagy is a major regulator of beta cell insulin homeostasis.

Riahi Y, Wikstrom JD, Bachar-Wikstrom E, Polin N, Zucker H, Lee MS, Quan W, Haataja L, Liu M, Arvan P, Cerasi E, Leibowitz G. Riahi Y, et al. Among authors: haataja l. Diabetologia. 2016 Jul;59(7):1480-1491. doi: 10.1007/s00125-016-3868-9. Epub 2016 Jan 30. Diabetologia. 2016. PMID: 26831301 Free PMC article.

2

Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth.

Liu M, Hodish I, Haataja L, Lara-Lemus R, Rajpal G, Wright J, Arvan P. Liu M, et al. Among authors: haataja l. Trends Endocrinol Metab. 2010 Nov;21(11):652-9. doi: 10.1016/j.tem.2010.07.001. Epub 2010 Aug 18. Trends Endocrinol Metab. 2010. PMID: 20724178 Free PMC article. Review.

3

Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport.

Liu M, Haataja L, Wright J, Wickramasinghe NP, Hua QX, Phillips NF, Barbetti F, Weiss MA, Arvan P. Liu M, et al. Among authors: haataja l. PLoS One. 2010 Oct 11;5(10):e13333. doi: 10.1371/journal.pone.0013333. PLoS One. 2010. PMID: 20948967 Free PMC article.

4

In vivo misfolding of proinsulin below the threshold of frank diabetes.

Hodish I, Absood A, Liu L, Liu M, Haataja L, Larkin D, Al-Khafaji A, Zaki A, Arvan P. Hodish I, et al. Among authors: haataja l. Diabetes. 2011 Aug;60(8):2092-101. doi: 10.2337/db10-1671. Epub 2011 Jun 15. Diabetes. 2011. PMID: 21677281 Free PMC article.

5

Impaired cleavage of preproinsulin signal peptide linked to autosomal-dominant diabetes.

Liu M, Lara-Lemus R, Shan SO, Wright J, Haataja L, Barbetti F, Guo H, Larkin D, Arvan P. Liu M, et al. Among authors: haataja l. Diabetes. 2012 Apr;61(4):828-37. doi: 10.2337/db11-0878. Epub 2012 Feb 22. Diabetes. 2012. PMID: 22357960 Free PMC article.

6

Proinsulin intermolecular interactions during secretory trafficking in pancreatic β cells.

Haataja L, Snapp E, Wright J, Liu M, Hardy AB, Wheeler MB, Markwardt ML, Rizzo MA, Arvan P. Haataja L, et al. J Biol Chem. 2013 Jan 18;288(3):1896-906. doi: 10.1074/jbc.M112.420018. Epub 2012 Dec 6. J Biol Chem. 2013. PMID: 23223446 Free PMC article.

7

Dominant protein interactions that influence the pathogenesis of conformational diseases.

Wright J, Wang X, Haataja L, Kellogg AP, Lee J, Liu M, Arvan P. Wright J, et al. Among authors: haataja l. J Clin Invest. 2013 Jul;123(7):3124-34. doi: 10.1172/JCI67260. Epub 2013 Jun 3. J Clin Invest. 2013. PMID: 23722904 Free PMC article.

8

Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress.

Wright J, Birk J, Haataja L, Liu M, Ramming T, Weiss MA, Appenzeller-Herzog C, Arvan P. Wright J, et al. Among authors: haataja l. J Biol Chem. 2013 Oct 25;288(43):31010-8. doi: 10.1074/jbc.M113.510065. Epub 2013 Sep 10. J Biol Chem. 2013. PMID: 24022479 Free PMC article.

9

Inefficient translocation of preproinsulin contributes to pancreatic β cell failure and late-onset diabetes.

Guo H, Xiong Y, Witkowski P, Cui J, Wang LJ, Sun J, Lara-Lemus R, Haataja L, Hutchison K, Shan SO, Arvan P, Liu M. Guo H, et al. Among authors: haataja l. J Biol Chem. 2014 Jun 6;289(23):16290-302. doi: 10.1074/jbc.M114.562355. Epub 2014 Apr 25. J Biol Chem. 2014. PMID: 24770419 Free PMC article.

10

Sox17 regulates insulin secretion in the normal and pathologic mouse β cell.

Jonatan D, Spence JR, Method AM, Kofron M, Sinagoga K, Haataja L, Arvan P, Deutsch GH, Wells JM. Jonatan D, et al. Among authors: haataja l. PLoS One. 2014 Aug 21;9(8):e104675. doi: 10.1371/journal.pone.0104675. eCollection 2014. PLoS One. 2014. PMID: 25144761 Free PMC article.

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