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Glutathione depletion is associated with augmenting a proinflammatory signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium.
Haddad JJ. Haddad JJ. Cytokines Cell Mol Ther. 2000 Dec;6(4):177-87. doi: 10.1080/mccm.6.4.177.187. Cytokines Cell Mol Ther. 2000. PMID: 11565956
A redox microenvironment is essential for MAPK-dependent secretion of pro-inflammatory cytokines: modulation by glutathione (GSH/GSSG) biosynthesis and equilibrium in the alveolar epithelium.
Haddad JJ. Haddad JJ. Cell Immunol. 2011;270(1):53-61. doi: 10.1016/j.cellimm.2011.04.001. Epub 2011 Apr 16. Cell Immunol. 2011. PMID: 21550026
On the cellular and molecular regulatory transcriptional mechanisms and responsive putative pathways to inflammatory oxidative stress revisited: current immunological breakthroughs and views at a glance.
Haddad JJ. Haddad JJ. Antiinflamm Antiallergy Agents Med Chem. 2013;12(2):141-57. doi: 10.2174/1871523011312020006. Antiinflamm Antiallergy Agents Med Chem. 2013. PMID: 23363382
The role of inflammatory cytokines and NF-kappaB/MAPK signaling pathways in the evolution of familial Mediterranean fever: current clinical perspectives and potential therapeutic approaches.
Haddad JJ. Haddad JJ. Cell Immunol. 2009;260(1):6-13. doi: 10.1016/j.cellimm.2009.08.003. Epub 2009 Aug 14. Cell Immunol. 2009. PMID: 19733345 Review.
NF-κB cellular and molecular regulatory mechanisms and pathways: therapeutic pattern or pseudoregulation?
Haddad JJ, Abdel-Karim NE. Haddad JJ, et al. Cell Immunol. 2011;271(1):5-14. doi: 10.1016/j.cellimm.2011.06.021. Epub 2011 Jun 26. Cell Immunol. 2011. PMID: 21777910 Review.
L-gamma-Glutamyl-L-cysteinyl-glycine (glutathione; GSH) and GSH-related enzymes in the regulation of pro- and anti-inflammatory cytokines: a signaling transcriptional scenario for redox(y) immunologic sensor(s)?
Haddad JJ, Harb HL. Haddad JJ, et al. Mol Immunol. 2005 May;42(9):987-1014. doi: 10.1016/j.molimm.2004.09.029. Epub 2004 Nov 23. Mol Immunol. 2005. PMID: 15829290 Review.
Oxygen sensing and oxidant/redox-related pathways.
Haddad JJ. Haddad JJ. Biochem Biophys Res Commun. 2004 Apr 16;316(4):969-77. doi: 10.1016/j.bbrc.2004.02.162. Biochem Biophys Res Commun. 2004. PMID: 15044079 Review.
Oxygen homeostasis, thiol equilibrium and redox regulation of signalling transcription factors in the alveolar epithelium.
Haddad JJ. Haddad JJ. Cell Signal. 2002 Oct;14(10):799-810. doi: 10.1016/s0898-6568(02)00022-0. Cell Signal. 2002. PMID: 12135701 Review.
Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors.
Haddad JJ. Haddad JJ. Cell Signal. 2002 Nov;14(11):879-97. doi: 10.1016/s0898-6568(02)00053-0. Cell Signal. 2002. PMID: 12220615 Review.
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