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The role of high-throughput technologies in clinical cancer genomics.
Idris SF, Ahmad SS, Scott MA, Vassiliou GS, Hadfield J. Idris SF, et al. Among authors: hadfield j. Expert Rev Mol Diagn. 2013 Mar;13(2):167-81. doi: 10.1586/erm.13.1. Expert Rev Mol Diagn. 2013. PMID: 23477557 Review.
Introduction to miRNA profiling technologies and cross-platform comparison.
Aldridge S, Hadfield J. Aldridge S, et al. Among authors: hadfield j. Methods Mol Biol. 2012;822:19-31. doi: 10.1007/978-1-61779-427-8_2. Methods Mol Biol. 2012. PMID: 22144189 Review.
A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.
Bruna A, Rueda OM, Greenwood W, Batra AS, Callari M, Batra RN, Pogrebniak K, Sandoval J, Cassidy JW, Tufegdzic-Vidakovic A, Sammut SJ, Jones L, Provenzano E, Baird R, Eirew P, Hadfield J, Eldridge M, McLaren-Douglas A, Barthorpe A, Lightfoot H, O'Connor MJ, Gray J, Cortes J, Baselga J, Marangoni E, Welm AL, Aparicio S, Serra V, Garnett MJ, Caldas C. Bruna A, et al. Among authors: hadfield j. Cell. 2016 Sep 22;167(1):260-274.e22. doi: 10.1016/j.cell.2016.08.041. Epub 2016 Sep 15. Cell. 2016. PMID: 27641504 Free PMC article.
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA.
Murtaza M, Dawson SJ, Tsui DW, Gale D, Forshew T, Piskorz AM, Parkinson C, Chin SF, Kingsbury Z, Wong AS, Marass F, Humphray S, Hadfield J, Bentley D, Chin TM, Brenton JD, Caldas C, Rosenfeld N. Murtaza M, et al. Among authors: hadfield j. Nature. 2013 May 2;497(7447):108-12. doi: 10.1038/nature12065. Epub 2013 Apr 7. Nature. 2013. PMID: 23563269
Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA.
Forshew T, Murtaza M, Parkinson C, Gale D, Tsui DW, Kaper F, Dawson SJ, Piskorz AM, Jimenez-Linan M, Bentley D, Hadfield J, May AP, Caldas C, Brenton JD, Rosenfeld N. Forshew T, et al. Among authors: hadfield j. Sci Transl Med. 2012 May 30;4(136):136ra68. doi: 10.1126/scitranslmed.3003726. Sci Transl Med. 2012. PMID: 22649089
ChIP-seq: using high-throughput sequencing to discover protein-DNA interactions.
Schmidt D, Wilson MD, Spyrou C, Brown GD, Hadfield J, Odom DT. Schmidt D, et al. Among authors: hadfield j. Methods. 2009 Jul;48(3):240-8. doi: 10.1016/j.ymeth.2009.03.001. Epub 2009 Mar 9. Methods. 2009. PMID: 19275939 Free PMC article.
A profusion of confusion in NGS methods naming.
Hadfield J, Retief J. Hadfield J, et al. Nat Methods. 2018 Jan 3;15(1):7-8. doi: 10.1038/nmeth.4558. Nat Methods. 2018. PMID: 29298293 No abstract available.
Mycoplasma genitalium: whole genome sequence analysis, recombination and population structure.
Fookes MC, Hadfield J, Harris S, Parmar S, Unemo M, Jensen JS, Thomson NR. Fookes MC, et al. Among authors: hadfield j. BMC Genomics. 2017 Dec 28;18(1):993. doi: 10.1186/s12864-017-4399-6. BMC Genomics. 2017. PMID: 29281972 Free PMC article.
The pitfalls of platform comparison: DNA copy number array technologies assessed.
Curtis C, Lynch AG, Dunning MJ, Spiteri I, Marioni JC, Hadfield J, Chin SF, Brenton JD, Tavaré S, Caldas C. Curtis C, et al. Among authors: hadfield j. BMC Genomics. 2009 Dec 8;10:588. doi: 10.1186/1471-2164-10-588. BMC Genomics. 2009. PMID: 19995423 Free PMC article.
Germline pathogenic variants in PALB2 and other cancer-predisposing genes in families with hereditary diffuse gastric cancer without CDH1 mutation: a whole-exome sequencing study.
Fewings E, Larionov A, Redman J, Goldgraben MA, Scarth J, Richardson S, Brewer C, Davidson R, Ellis I, Evans DG, Halliday D, Izatt L, Marks P, McConnell V, Verbist L, Mayes R, Clark GR, Hadfield J, Chin SF, Teixeira MR, Giger OT, Hardwick R, di Pietro M, O'Donovan M, Pharoah P, Caldas C, Fitzgerald RC, Tischkowitz M. Fewings E, et al. Among authors: hadfield j. Lancet Gastroenterol Hepatol. 2018 Jul;3(7):489-498. doi: 10.1016/S2468-1253(18)30079-7. Epub 2018 Apr 27. Lancet Gastroenterol Hepatol. 2018. PMID: 29706558 Free PMC article.
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