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Drug interactions with phytotherapeutics in oncology.
Haefeli WE, Carls A. Haefeli WE, et al. Expert Opin Drug Metab Toxicol. 2014 Mar;10(3):359-77. doi: 10.1517/17425255.2014.873786. Epub 2014 Jan 6. Expert Opin Drug Metab Toxicol. 2014. PMID: 24387348 Review.
[Drug interactions with the cytochrome P-450 system].
Martin-Facklam M, Drewe J, Haefeli WE. Martin-Facklam M, et al. Dtsch Med Wochenschr. 2000 Jan 21;125(3):63-7. doi: 10.1055/s-2007-1023908. Dtsch Med Wochenschr. 2000. PMID: 10682001 Review. German. No abstract available.
[Individualized drug therapy--need for improvement].
Haefeli WE. Haefeli WE. Ther Umsch. 2000 Sep;57(9):545-6. doi: 10.1024/0040-5930.57.9.545. Ther Umsch. 2000. PMID: 11036432 German.
[Clinically relevant adverse drug interactions].
Martin-Facklam M, Haefeli WE. Martin-Facklam M, et al. Ther Umsch. 2000 Sep;57(9):579-83. doi: 10.1024/0040-5930.57.9.579. Ther Umsch. 2000. PMID: 11036439 Review. German.
Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL.
Martin-Facklam M, Burhenne J, Ding R, Fricker R, Mikus G, Walter-Sack I, Haefeli WE. Martin-Facklam M, et al. Br J Clin Pharmacol. 2002 Jun;53(6):576-81. doi: 10.1046/j.1365-2125.2002.01595.x. Br J Clin Pharmacol. 2002. PMID: 12047481 Free PMC article. Clinical Trial.
Quality markers of drug information on the Internet: an evaluation of sites about St. John's wort.
Martin-Facklam M, Kostrzewa M, Schubert F, Gasse C, Haefeli WE. Martin-Facklam M, et al. Am J Med. 2002 Dec 15;113(9):740-5. doi: 10.1016/s0002-9343(02)01256-1. Am J Med. 2002. PMID: 12517364
PURPOSE: We aimed to evaluate websites about St. John's wort for the quality of their content, including accuracy as reflected by statement of correct indication and mentioning of interacting drugs, the presence of formal criteria as reflected by adherence to published sta …
PURPOSE: We aimed to evaluate websites about St. John's wort for the quality of their content, including accuracy as reflected by sta …
Inhibition of P-glycoprotein by newer antidepressants.
Weiss J, Dormann SM, Martin-Facklam M, Kerpen CJ, Ketabi-Kiyanvash N, Haefeli WE. Weiss J, et al. J Pharmacol Exp Ther. 2003 Apr;305(1):197-204. doi: 10.1124/jpet.102.046532. J Pharmacol Exp Ther. 2003. PMID: 12649369
To study possible interactions caused by the newer antidepressants we investigated citalopram, fluoxetine, fluvoxamine, paroxetine, reboxetine, sertraline, and venlafaxine and their major metabolites desmethylcitalopram, norfluoxetine, paroxetine-metabolite (paroxetine-M), …
To study possible interactions caused by the newer antidepressants we investigated citalopram, fluoxetine, fluvoxamine, paroxetine, r …
Interaction of antiepileptic drugs with human P-glycoprotein in vitro.
Weiss J, Kerpen CJ, Lindenmaier H, Dormann SM, Haefeli WE. Weiss J, et al. J Pharmacol Exp Ther. 2003 Oct;307(1):262-7. doi: 10.1124/jpet.103.054197. Epub 2003 Sep 3. J Pharmacol Exp Ther. 2003. PMID: 12954800
Therefore, we investigated whether AEDs commonly used in mono or add-on therapy inhibit Pgp using a calcein acetoxymethylester uptake assay with L-MDR1 cells and primary porcine brain capillary endothelial cells, as well as confocal laser-scanning microscopy with L-MDR1 ce …
Therefore, we investigated whether AEDs commonly used in mono or add-on therapy inhibit Pgp using a calcein acetoxymethylester uptake …
Influence of lipid lowering fibrates on P-glycoprotein activity in vitro.
Ehrhardt M, Lindenmaier H, Burhenne J, Haefeli WE, Weiss J. Ehrhardt M, et al. Biochem Pharmacol. 2004 Jan 15;67(2):285-92. doi: 10.1016/j.bcp.2003.09.008. Biochem Pharmacol. 2004. PMID: 14698041
We tested whether gemfibrozil, fenofibrate, fenofibric acid, and bezafibrate inhibit Pgp in vitro using a calcein acetoxymethylester (calcein-AM) uptake assay and confocal laser scanning microscopy with bodipy-verapamil as substrate in L-MDR1 cells, which overexpress human
We tested whether gemfibrozil, fenofibrate, fenofibric acid, and bezafibrate inhibit Pgp in vitro using a calcein acetoxymethylester
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