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Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice.
Fox BM, Gil HW, Kirkbride-Romeo L, Bagchi RA, Wennersten SA, Haefner KR, Skrypnyk NI, Brown CN, Soranno DE, Gist KM, Griffin BR, Jovanovich A, Reisz JA, Wither MJ, D'Alessandro A, Edelstein CL, Clendenen N, McKinsey TA, Altmann C, Faubel S. Fox BM, et al. Among authors: haefner kr. Kidney Int. 2019 Mar;95(3):590-610. doi: 10.1016/j.kint.2018.10.020. Epub 2019 Jan 30. Kidney Int. 2019. PMID: 30709662 Free PMC article.
Female and male mice have differential longterm cardiorenal outcomes following a matched degree of ischemia-reperfusion acute kidney injury.
Soranno DE, Baker P 2nd, Kirkbride-Romeo L, Wennersten SA, Ding K, Keith B, Cavasin MA, Altmann C, Bagchi RA, Haefner KR, Montford J, Gist KM, Vergnes L, Reue K, He Z, Elajaili H, Okamura K, Nozik E, McKinsey TA, Faubel S. Soranno DE, et al. Among authors: haefner kr. Sci Rep. 2022 Jan 12;12(1):643. doi: 10.1038/s41598-021-04701-x. Sci Rep. 2022. PMID: 35022484 Free PMC article.
Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition.
Soranno DE, Kirkbride-Romeo L, Wennersten SA, Ding K, Cavasin MA, Baker P, Altmann C, Bagchi RA, Haefner KR, Steinkühler C, Montford JR, Keith B, Gist KM, McKinsey TA, Faubel S. Soranno DE, et al. Among authors: haefner kr. JACC Basic Transl Sci. 2021 Feb 22;6(2):119-133. doi: 10.1016/j.jacbts.2020.11.013. eCollection 2021 Feb. JACC Basic Transl Sci. 2021. PMID: 33665513 Free PMC article.
HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin YH, Major JL, Liebner T, Hourani Z, Travers JG, Wennersten SA, Haefner KR, Cavasin MA, Wilson CE, Jeong MY, Han Y, Gotthardt M, Ferguson SK, Ambardekar AV, Lam MP, Choudhary C, Granzier HL, Woulfe KC, McKinsey TA. Lin YH, et al. Among authors: haefner kr. J Clin Invest. 2022 May 16;132(10):e148333. doi: 10.1172/JCI148333. J Clin Invest. 2022. PMID: 35575093 Free PMC article.