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Strategies based on organ decellularization and recellularization.
Hillebrandt KH, Everwien H, Haep N, Keshi E, Pratschke J, Sauer IM. Hillebrandt KH, et al. Among authors: haep n. Transpl Int. 2019 Jun;32(6):571-585. doi: 10.1111/tri.13462. Transpl Int. 2019. PMID: 31099920 Free article. Review.
Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans.
Napierala H, Hillebrandt KH, Haep N, Tang P, Tintemann M, Gassner J, Noesser M, Everwien H, Seiffert N, Kluge M, Teegen E, Polenz D, Lippert S, Geisel D, Reutzel Selke A, Raschzok N, Andreou A, Pratschke J, Sauer IM, Struecker B. Napierala H, et al. Among authors: haep n. Sci Rep. 2017 Feb 2;7:41777. doi: 10.1038/srep41777. Sci Rep. 2017. PMID: 28150744 Free PMC article.
Engineering an endothelialized, endocrine Neo-Pancreas: Evaluation of islet functionality in an ex vivo model.
Everwien H, Keshi E, Hillebrandt KH, Ludwig B, Weinhart M, Tang P, Beierle AS, Napierala H, Gassner JM, Seiffert N, Moosburner S, Geisel D, Reutzel-Selke A, Strücker B, Pratschke J, Haep N, Sauer IM. Everwien H, et al. Among authors: haep n. Acta Biomater. 2020 Nov;117:213-225. doi: 10.1016/j.actbio.2020.09.022. Epub 2020 Sep 16. Acta Biomater. 2020. PMID: 32949822
Molecular overview of progressive familial intrahepatic cholestasis.
Amirneni S, Haep N, Gad MA, Soto-Gutierrez A, Squires JE, Florentino RM. Amirneni S, et al. Among authors: haep n. World J Gastroenterol. 2020 Dec 21;26(47):7470-7484. doi: 10.3748/wjg.v26.i47.7470. World J Gastroenterol. 2020. PMID: 33384548 Free PMC article. Review.
Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells.
Takeishi K, Collin de l'Hortet A, Wang Y, Handa K, Guzman-Lepe J, Matsubara K, Morita K, Jang S, Haep N, Florentino RM, Yuan F, Fukumitsu K, Tobita K, Sun W, Franks J, Delgado ER, Shapiro EM, Fraunhoffer NA, Duncan AW, Yagi H, Mashimo T, Fox IJ, Soto-Gutierrez A. Takeishi K, et al. Among authors: haep n. Cell Rep. 2020 Jun 2;31(9):107711. doi: 10.1016/j.celrep.2020.107711. Cell Rep. 2020. PMID: 32492423 Free PMC article.
Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans.
Florentino RM, Fraunhoffer NA, Morita K, Takeishi K, Ostrowska A, Achreja A, Animasahun O, Haep N, Arazov S, Agarwal N, Collin de l'Hortet A, Guzman-Lepe J, Tafaleng EN, Mukherjee A, Troy K, Banerjee S, Paranjpe S, Michalopoulos GK, Bell A, Nagrath D, Hainer SJ, Fox IJ, Soto-Gutierrez A. Florentino RM, et al. Among authors: haep n. Hepatol Commun. 2020 Apr 21;4(6):859-875. doi: 10.1002/hep4.1505. eCollection 2020 Jun. Hepatol Commun. 2020. PMID: 32490322 Free PMC article.