Haffke M - Search Results

1

Structural basis of species-selective antagonist binding to the succinate receptor.

Haffke M, Fehlmann D, Rummel G, Boivineau J, Duckely M, Gommermann N, Cotesta S, Sirockin F, Freuler F, Littlewood-Evans A, Kaupmann K, Jaakola VP. Haffke M, et al. Nature. 2019 Oct;574(7779):581-585. doi: 10.1038/s41586-019-1663-8. Epub 2019 Oct 23. Nature. 2019. PMID: 31645725

2

Development of a biochemical and biophysical suite for integral membrane protein targets: A review.

Haffke M, Duckely M, Bergsdorf C, Jaakola VP, Shrestha B. Haffke M, et al. Protein Expr Purif. 2020 Mar;167:105545. doi: 10.1016/j.pep.2019.105545. Epub 2019 Nov 26. Protein Expr Purif. 2020. PMID: 31778786 Review.

3

Membrane Protein Expression in Insect Cells Using the Baculovirus Expression Vector System.

Boivineau J, Haffke M, Jaakola VP. Boivineau J, et al. Among authors: haffke m. Methods Mol Biol. 2020;2127:63-80. doi: 10.1007/978-1-0716-0373-4_5. Methods Mol Biol. 2020. PMID: 32112315

4

Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure.

Velcicky J, Wilcken R, Cotesta S, Janser P, Schlapbach A, Wagner T, Piechon P, Villard F, Bouhelal R, Piller F, Harlfinger S, Stringer R, Fehlmann D, Kaupmann K, Littlewood-Evans A, Haffke M, Gommermann N. Velcicky J, et al. Among authors: haffke m. J Med Chem. 2020 Sep 10;63(17):9856-9875. doi: 10.1021/acs.jmedchem.0c01020. Epub 2020 Aug 28. J Med Chem. 2020. PMID: 32856916

5

Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly.

Antonova SV, Haffke M, Corradini E, Mikuciunas M, Low TY, Signor L, van Es RM, Gupta K, Scheer E, Vos HR, Tora L, Heck AJR, Timmers HTM, Berger I. Antonova SV, et al. Among authors: haffke m. Nat Struct Mol Biol. 2018 Dec;25(12):1119-1127. doi: 10.1038/s41594-018-0156-z. Epub 2018 Dec 3. Nat Struct Mol Biol. 2018. PMID: 30510221 Free PMC article.

6

Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.

Trowitzsch S, Viola C, Scheer E, Conic S, Chavant V, Fournier M, Papai G, Ebong IO, Schaffitzel C, Zou J, Haffke M, Rappsilber J, Robinson CV, Schultz P, Tora L, Berger I. Trowitzsch S, et al. Among authors: haffke m. Nat Commun. 2015 Jan 14;6:6011. doi: 10.1038/ncomms7011. Nat Commun. 2015. PMID: 25586196 Free PMC article.

7

Zooming in on Transcription Preinitiation.

Gupta K, Sari-Ak D, Haffke M, Trowitzsch S, Berger I. Gupta K, et al. Among authors: haffke m. J Mol Biol. 2016 Jun 19;428(12):2581-2591. doi: 10.1016/j.jmb.2016.04.003. Epub 2016 Apr 8. J Mol Biol. 2016. PMID: 27067110 Free PMC article. Review.

8

More pieces to the puzzle: recent structural insights into class II transcription initiation.

Kandiah E, Trowitzsch S, Gupta K, Haffke M, Berger I. Kandiah E, et al. Among authors: haffke m. Curr Opin Struct Biol. 2014 Feb;24:91-7. doi: 10.1016/j.sbi.2013.12.005. Epub 2014 Jan 16. Curr Opin Struct Biol. 2014. PMID: 24440461 Review.

9

Tandem recombineering by SLIC cloning and Cre-LoxP fusion to generate multigene expression constructs for protein complex research.

Haffke M, Viola C, Nie Y, Berger I. Haffke M, et al. Methods Mol Biol. 2013;1073:131-40. doi: 10.1007/978-1-62703-625-2_11. Methods Mol Biol. 2013. PMID: 23996444

10

The multiBac protein complex production platform at the EMBL.

Berger I, Garzoni F, Chaillet M, Haffke M, Gupta K, Aubert A. Berger I, et al. Among authors: haffke m. J Vis Exp. 2013 Jul 11;(77):e50159. doi: 10.3791/50159. J Vis Exp. 2013. PMID: 23892976 Free PMC article.

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