Hafner M - Search Results

1

Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling.

Niepel M, Hafner M, Duan Q, Wang Z, Paull EO, Chung M, Lu X, Stuart JM, Golub TR, Subramanian A, Ma'ayan A, Sorger PK. Niepel M, et al. Among authors: hafner m. Nat Commun. 2017 Oct 30;8(1):1186. doi: 10.1038/s41467-017-01383-w. Nat Commun. 2017. PMID: 29084964 Free PMC article.

2

Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines.

Niepel M, Hafner M, Pace EA, Chung M, Chai DH, Zhou L, Schoeberl B, Sorger PK. Niepel M, et al. Among authors: hafner m. Sci Signal. 2013 Sep 24;6(294):ra84. doi: 10.1126/scisignal.2004379. Sci Signal. 2013. PMID: 24065145 Free PMC article.

3

Analysis of growth factor signaling in genetically diverse breast cancer lines.

Niepel M, Hafner M, Pace EA, Chung M, Chai DH, Zhou L, Muhlich JL, Schoeberl B, Sorger PK. Niepel M, et al. Among authors: hafner m. BMC Biol. 2014 Mar 21;12:20. doi: 10.1186/1741-7007-12-20. BMC Biol. 2014. PMID: 24655548 Free PMC article.

4

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.

Duan Q, Flynn C, Niepel M, Hafner M, Muhlich JL, Fernandez NF, Rouillard AD, Tan CM, Chen EY, Golub TR, Sorger PK, Subramanian A, Ma'ayan A. Duan Q, et al. Among authors: hafner m. Nucleic Acids Res. 2014 Jul;42(Web Server issue):W449-60. doi: 10.1093/nar/gku476. Epub 2014 Jun 6. Nucleic Acids Res. 2014. PMID: 24906883 Free PMC article.

5

Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold.

Roux J, Hafner M, Bandara S, Sims JJ, Hudson H, Chai D, Sorger PK. Roux J, et al. Among authors: hafner m. Mol Syst Biol. 2015 May 7;11(5):803. doi: 10.15252/msb.20145584. Mol Syst Biol. 2015. PMID: 25953765 Free PMC article.

6

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs.

Hafner M, Niepel M, Chung M, Sorger PK. Hafner M, et al. Nat Methods. 2016 Jun;13(6):521-7. doi: 10.1038/nmeth.3853. Epub 2016 May 2. Nat Methods. 2016. PMID: 27135972 Free PMC article.

7

L1000CDS²: LINCS L1000 characteristic direction signatures search engine.

Duan Q, Reid SP, Clark NR, Wang Z, Fernandez NF, Rouillard AD, Readhead B, Tritsch SR, Hodos R, Hafner M, Niepel M, Sorger PK, Dudley JT, Bavari S, Panchal RG, Ma'ayan A. Duan Q, et al. Among authors: hafner m. NPJ Syst Biol Appl. 2016;2:16015-. doi: 10.1038/npjsba.2016.15. Epub 2016 Aug 4. NPJ Syst Biol Appl. 2016. PMID: 28413689 Free PMC article.

8

Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics.

Hafner M, Niepel M, Sorger PK. Hafner M, et al. Nat Biotechnol. 2017 Jun 7;35(6):500-502. doi: 10.1038/nbt.3882. Nat Biotechnol. 2017. PMID: 28591115 Free PMC article. No abstract available.

9

Measuring Cancer Drug Sensitivity and Resistance in Cultured Cells.

Niepel M, Hafner M, Chung M, Sorger PK. Niepel M, et al. Among authors: hafner m. Curr Protoc Chem Biol. 2017 Jun 19;9(2):55-74. doi: 10.1002/cpch.21. Curr Protoc Chem Biol. 2017. PMID: 28628199 Free PMC article.

10

Designing Drug-Response Experiments and Quantifying their Results.

Hafner M, Niepel M, Subramanian K, Sorger PK. Hafner M, et al. Curr Protoc Chem Biol. 2017 Jun 19;9(2):96-116. doi: 10.1002/cpch.19. Curr Protoc Chem Biol. 2017. PMID: 28628201 Free PMC article.

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