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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 2
2000 2
2003 5
2004 3
2005 2
2006 2
2007 2
2008 1
2009 5
2010 12
2011 10
2012 9
2013 12
2014 14
2015 8
2016 14
2017 17
2018 9
2019 17
2020 12
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140 results
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Page 1
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
Subramanian A, Narayan R, Corsello SM, Peck DD, Natoli TE, Lu X, Gould J, Davis JF, Tubelli AA, Asiedu JK, Lahr DL, Hirschman JE, Liu Z, Donahue M, Julian B, Khan M, Wadden D, Smith IC, Lam D, Liberzon A, Toder C, Bagul M, Orzechowski M, Enache OM, Piccioni F, Johnson SA, Lyons NJ, Berger AH, Shamji AF, Brooks AN, Vrcic A, Flynn C, Rosains J, Takeda DY, Hu R, Davison D, Lamb J, Ardlie K, Hogstrom L, Greenside P, Gray NS, Clemons PA, Silver S, Wu X, Zhao WN, Read-Button W, Wu X, Haggarty SJ, Ronco LV, Boehm JS, Schreiber SL, Doench JG, Bittker JA, Root DE, Wong B, Golub TR. Subramanian A, et al. Among authors: haggarty sj. Cell. 2017 Nov 30;171(6):1437-1452.e17. doi: 10.1016/j.cell.2017.10.049. Cell. 2017. PMID: 29195078 Free PMC article.
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, Lerner J, Brunet JP, Subramanian A, Ross KN, Reich M, Hieronymus H, Wei G, Armstrong SA, Haggarty SJ, Clemons PA, Wei R, Carr SA, Lander ES, Golub TR. Lamb J, et al. Among authors: haggarty sj. Science. 2006 Sep 29;313(5795):1929-35. doi: 10.1126/science.1132939. Science. 2006. PMID: 17008526 Free article.
Classics in Chemical Neuroscience: Haloperidol.
Tyler MW, Zaldivar-Diez J, Haggarty SJ. Tyler MW, et al. Among authors: haggarty sj. ACS Chem Neurosci. 2017 Mar 15;8(3):444-453. doi: 10.1021/acschemneuro.7b00018. Epub 2017 Feb 15. ACS Chem Neurosci. 2017. PMID: 28170220
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
Swarup V, Hinz FI, Rexach JE, Noguchi KI, Toyoshiba H, Oda A, Hirai K, Sarkar A, Seyfried NT, Cheng C, Haggarty SJ; International Frontotemporal Dementia Genomics Consortium, Grossman M, Van Deerlin VM, Trojanowski JQ, Lah JJ, Levey AI, Kondou S, Geschwind DH. Swarup V, et al. Among authors: haggarty sj. Nat Med. 2019 Jan;25(1):152-164. doi: 10.1038/s41591-018-0223-3. Epub 2018 Dec 3. Nat Med. 2019. PMID: 30510257 Free PMC article.
HDAC2 negatively regulates memory formation and synaptic plasticity.
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH. Guan JS, et al. Among authors: haggarty sj. Nature. 2009 May 7;459(7243):55-60. doi: 10.1038/nature07925. Nature. 2009. PMID: 19424149 Free PMC article.
A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies.
Karch CM, Kao AW, Karydas A, Onanuga K, Martinez R, Argouarch A, Wang C, Huang C, Sohn PD, Bowles KR, Spina S, Silva MC, Marsh JA, Hsu S, Pugh DA, Ghoshal N, Norton J, Huang Y, Lee SE, Seeley WW, Theofilas P, Grinberg LT, Moreno F, McIlroy K, Boeve BF, Cairns NJ, Crary JF, Haggarty SJ, Ichida JK, Kosik KS, Miller BL, Gan L, Goate AM, Temple S; Tau Consortium Stem Cell Group. Karch CM, et al. Among authors: haggarty sj. Stem Cell Reports. 2019 Nov 12;13(5):939-955. doi: 10.1016/j.stemcr.2019.09.006. Epub 2019 Oct 17. Stem Cell Reports. 2019. PMID: 31631020 Free PMC article.
Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models.
Silva MC, Ferguson FM, Cai Q, Donovan KA, Nandi G, Patnaik D, Zhang T, Huang HT, Lucente DE, Dickerson BC, Mitchison TJ, Fischer ES, Gray NS, Haggarty SJ. Silva MC, et al. Among authors: haggarty sj. Elife. 2019 Mar 25;8:e45457. doi: 10.7554/eLife.45457. Elife. 2019. PMID: 30907729 Free PMC article.
Human pluripotent stem cell-derived models and drug screening in CNS precision medicine.
Silva MC, Haggarty SJ. Silva MC, et al. Among authors: haggarty sj. Ann N Y Acad Sci. 2020 Jul;1471(1):18-56. doi: 10.1111/nyas.14012. Epub 2019 Mar 15. Ann N Y Acad Sci. 2020. PMID: 30875083 Review.
MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling.
Mellios N, Feldman DA, Sheridan SD, Ip JPK, Kwok S, Amoah SK, Rosen B, Rodriguez BA, Crawford B, Swaminathan R, Chou S, Li Y, Ziats M, Ernst C, Jaenisch R, Haggarty SJ, Sur M. Mellios N, et al. Among authors: haggarty sj. Mol Psychiatry. 2018 Apr;23(4):1051-1065. doi: 10.1038/mp.2017.86. Epub 2017 Apr 25. Mol Psychiatry. 2018. PMID: 28439102 Free PMC article.
A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy.
Hernandez I, Luna G, Rauch JN, Reis SA, Giroux M, Karch CM, Boctor D, Sibih YE, Storm NJ, Diaz A, Kaushik S, Zekanowski C, Kang AA, Hinman CR, Cerovac V, Guzman E, Zhou H, Haggarty SJ, Goate AM, Fisher SK, Cuervo AM, Kosik KS. Hernandez I, et al. Among authors: haggarty sj. Sci Transl Med. 2019 Mar 27;11(485):eaat3005. doi: 10.1126/scitranslmed.aat3005. Sci Transl Med. 2019. PMID: 30918111
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