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19 results
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Hypoxia-inducible factor-1α (HIF-1α) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions.
Yi T, Papadopoulos E, Hagner PR, Wagner G. Yi T, et al. Among authors: hagner pr. J Biol Chem. 2013 Jun 28;288(26):18732-42. doi: 10.1074/jbc.M113.471466. Epub 2013 May 10. J Biol Chem. 2013. PMID: 23667251 Free PMC article.
The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β.
Luna RE, Arthanari H, Hiraishi H, Nanda J, Martin-Marcos P, Markus MA, Akabayov B, Milbradt AG, Luna LE, Seo HC, Hyberts SG, Fahmy A, Reibarkh M, Miles D, Hagner PR, O'Day EM, Yi T, Marintchev A, Hinnebusch AG, Lorsch JR, Asano K, Wagner G. Luna RE, et al. Among authors: hagner pr. Cell Rep. 2012 Jun 28;1(6):689-702. doi: 10.1016/j.celrep.2012.04.007. Epub 2012 May 24. Cell Rep. 2012. PMID: 22813744 Free PMC article.
Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype.
Mazan-Mamczarz K, Hagner PR, Corl S, Srikantan S, Wood WH, Becker KG, Gorospe M, Keene JD, Levenson AS, Gartenhaus RB. Mazan-Mamczarz K, et al. Among authors: hagner pr. Oncogene. 2008 Oct 16;27(47):6151-63. doi: 10.1038/onc.2008.215. Epub 2008 Jul 21. Oncogene. 2008. PMID: 18641687 Free PMC article.
ATM regulates a DNA damage response posttranscriptional RNA operon in lymphocytes.
Mazan-Mamczarz K, Hagner PR, Zhang Y, Dai B, Lehrmann E, Becker KG, Keene JD, Gorospe M, Liu Z, Gartenhaus RB. Mazan-Mamczarz K, et al. Among authors: hagner pr. Blood. 2011 Feb 24;117(8):2441-50. doi: 10.1182/blood-2010-09-310987. Epub 2011 Jan 5. Blood. 2011. PMID: 21209379 Free PMC article.
Targeting the translational machinery as a novel treatment strategy for hematologic malignancies.
Hagner PR, Schneider A, Gartenhaus RB. Hagner PR, et al. Blood. 2010 Mar 18;115(11):2127-35. doi: 10.1182/blood-2009-09-220020. Epub 2010 Jan 14. Blood. 2010. PMID: 20075156 Free PMC article. Review.
Identification of transformation-related pathways in a breast epithelial cell model using a ribonomics approach.
Mazan-Mamczarz K, Hagner PR, Dai B, Wood WH, Zhang Y, Becker KG, Liu Z, Gartenhaus RB. Mazan-Mamczarz K, et al. Among authors: hagner pr. Cancer Res. 2008 Oct 1;68(19):7730-5. doi: 10.1158/0008-5472.CAN-08-2393. Cancer Res. 2008. PMID: 18829526 Free PMC article.
Alcohol consumption and decreased risk of non-Hodgkin lymphoma: role of mTOR dysfunction.
Hagner PR, Mazan-Mamczarz K, Dai B, Corl S, Zhao XF, Gartenhaus RB. Hagner PR, et al. Blood. 2009 May 28;113(22):5526-35. doi: 10.1182/blood-2008-11-191783. Epub 2009 Mar 17. Blood. 2009. PMID: 19293424
Ribosomal protein S6 is highly expressed in non-Hodgkin lymphoma and associates with mRNA containing a 5' terminal oligopyrimidine tract.
Hagner PR, Mazan-Mamczarz K, Dai B, Balzer EM, Corl S, Martin SS, Zhao XF, Gartenhaus RB. Hagner PR, et al. Oncogene. 2011 Mar 31;30(13):1531-41. doi: 10.1038/onc.2010.533. Epub 2010 Nov 22. Oncogene. 2011. PMID: 21102526 Free PMC article.
CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL.
Hagner PR, Man HW, Fontanillo C, Wang M, Couto S, Breider M, Bjorklund C, Havens CG, Lu G, Rychak E, Raymon H, Narla RK, Barnes L, Khambatta G, Chiu H, Kosek J, Kang J, Amantangelo MD, Waldman M, Lopez-Girona A, Cai T, Pourdehnad M, Trotter M, Daniel TO, Schafer PH, Klippel A, Thakurta A, Chopra R, Gandhi AK. Hagner PR, et al. Blood. 2015 Aug 6;126(6):779-89. doi: 10.1182/blood-2015-02-628669. Epub 2015 May 22. Blood. 2015. PMID: 26002965 Free PMC article. Clinical Trial.
Functional and molecular interactions between ERK and CHK2 in diffuse large B-cell lymphoma.
Dai B, Zhao XF, Mazan-Mamczarz K, Hagner P, Corl S, Bahassi el M, Lu S, Stambrook PJ, Shapiro P, Gartenhaus RB. Dai B, et al. Nat Commun. 2011 Jul 19;2:402. doi: 10.1038/ncomms1404. Nat Commun. 2011. PMID: 21772273 Free PMC article.
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