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Rules for making human tumor cells.
Hahn WC, Weinberg RA. Hahn WC, et al. N Engl J Med. 2002 Nov 14;347(20):1593-603. doi: 10.1056/NEJMra021902. N Engl J Med. 2002. PMID: 12432047 Review. No abstract available.
Overlapping but nonidentical binding sites on CD2 for CD58 and a second ligand CD59.
Hahn WC, Menu E, Bothwell AL, Sims PJ, Bierer BE. Hahn WC, et al. Science. 1992 Jun 26;256(5065):1805-7. doi: 10.1126/science.1377404. Science. 1992. PMID: 1377404
Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation.
Hahn WC, Bierer BE. Hahn WC, et al. J Exp Med. 1993 Nov 1;178(5):1831-6. doi: 10.1084/jem.178.5.1831. J Exp Med. 1993. PMID: 7901319 Free PMC article.
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics.
Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG. Dickson MA, et al. Among authors: hahn wc. Mol Cell Biol. 2000 Feb;20(4):1436-47. doi: 10.1128/mcb.20.4.1436-1447.2000. Mol Cell Biol. 2000. PMID: 10648628 Free PMC article.
Telomerase activation, cellular immortalization and cancer.
Hahn WC, Meyerson M. Hahn WC, et al. Ann Med. 2001 Mar;33(2):123-9. doi: 10.3109/07853890109002067. Ann Med. 2001. PMID: 11327115 Review.
Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase.
Vonderheide RH, Anderson KS, Hahn WC, Butler MO, Schultze JL, Nadler LM. Vonderheide RH, et al. Among authors: hahn wc. Clin Cancer Res. 2001 Nov;7(11):3343-8. Clin Cancer Res. 2001. PMID: 11705846
Derivation of human tumor cells in vitro without widespread genomic instability.
Zimonjic D, Brooks MW, Popescu N, Weinberg RA, Hahn WC. Zimonjic D, et al. Among authors: hahn wc. Cancer Res. 2001 Dec 15;61(24):8838-44. Cancer Res. 2001. PMID: 11751406
Modelling the molecular circuitry of cancer.
Hahn WC, Weinberg RA. Hahn WC, et al. Nat Rev Cancer. 2002 May;2(5):331-41. doi: 10.1038/nrc795. Nat Rev Cancer. 2002. PMID: 12044009 Review.
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status.
Rheinwald JG, Hahn WC, Ramsey MR, Wu JY, Guo Z, Tsao H, De Luca M, Catricalà C, O'Toole KM. Rheinwald JG, et al. Among authors: hahn wc. Mol Cell Biol. 2002 Jul;22(14):5157-72. doi: 10.1128/mcb.22.14.5157-5172.2002. Mol Cell Biol. 2002. PMID: 12077343 Free PMC article.
Immortalization and transformation of human cells.
Hahn WC. Hahn WC. Mol Cells. 2002 Jun 30;13(3):351-61. Mol Cells. 2002. PMID: 12132573 Review.
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