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Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as important viral host factors.
Nuss JE, Kehn-Hall K, Benedict A, Costantino J, Ward M, Peyser BD, Retterer CJ, Tressler LE, Wanner LM, McGovern HF, Zaidi A, Anthony SM, Kota KP, Bavari S, Hakami RM. Nuss JE, et al. Among authors: hakami rm. PLoS One. 2014 May 8;9(5):e93483. doi: 10.1371/journal.pone.0093483. eCollection 2014. PLoS One. 2014. PMID: 24809507 Free PMC article.
Host response during Yersinia pestis infection of human bronchial epithelial cells involves negative regulation of autophagy and suggests a modulation of survival-related and cellular growth pathways.
Alem F, Yao K, Lane D, Calvert V, Petricoin EF, Kramer L, Hale ML, Bavari S, Panchal RG, Hakami RM. Alem F, et al. Among authors: hakami rm. Front Microbiol. 2015 Feb 13;6:50. doi: 10.3389/fmicb.2015.00050. eCollection 2015. Front Microbiol. 2015. PMID: 25762983 Free PMC article.
Protein Phosphatase-1 regulates Rift Valley fever virus replication.
Baer A, Shafagati N, Benedict A, Ammosova T, Ivanov A, Hakami RM, Terasaki K, Makino S, Nekhai S, Kehn-Hall K. Baer A, et al. Among authors: hakami rm. Antiviral Res. 2016 Mar;127:79-89. doi: 10.1016/j.antiviral.2016.01.007. Epub 2016 Jan 20. Antiviral Res. 2016. PMID: 26801627 Free PMC article.
Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1.
Yi F, Guo J, Dabbagh D, Spear M, He S, Kehn-Hall K, Fontenot J, Yin Y, Bibian M, Park CM, Zheng K, Park HJ, Soloveva V, Gharaibeh D, Retterer C, Zamani R, Pitt ML, Naughton J, Jiang Y, Shang H, Hakami RM, Ling B, Young JAT, Bavari S, Xu X, Feng Y, Wu Y. Yi F, et al. Among authors: hakami rm. J Virol. 2017 Jun 9;91(13):e02418-16. doi: 10.1128/JVI.02418-16. Print 2017 Jul 1. J Virol. 2017. PMID: 28381571 Free PMC article.
Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activation of autophagy.
Alem F, Olanrewaju AA, Omole S, Hobbs HE, Ahsan N, Matulis G, Brantner CA, Zhou W, Petricoin EF, Liotta LA, Caputi M, Bavari S, Wu Y, Kashanchi F, Hakami RM. Alem F, et al. Among authors: hakami rm. Cell Biosci. 2021 Dec 25;11(1):220. doi: 10.1186/s13578-021-00732-z. Cell Biosci. 2021. PMID: 34953502 Free PMC article.
Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA.
Narayanan A, Iordanskiy S, Das R, Van Duyne R, Santos S, Jaworski E, Guendel I, Sampey G, Dalby E, Iglesias-Ussel M, Popratiloff A, Hakami R, Kehn-Hall K, Young M, Subra C, Gilbert C, Bailey C, Romerio F, Kashanchi F. Narayanan A, et al. J Biol Chem. 2013 Jul 5;288(27):20014-33. doi: 10.1074/jbc.M112.438895. Epub 2013 May 9. J Biol Chem. 2013. PMID: 23661700 Free PMC article.
32 results