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Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity.
Salmena L, Lemmers B, Hakem A, Matysiak-Zablocki E, Murakami K, Au PY, Berry DM, Tamblyn L, Shehabeldin A, Migon E, Wakeham A, Bouchard D, Yeh WC, McGlade JC, Ohashi PS, Hakem R. Salmena L, et al. Among authors: hakem a, hakem r. Genes Dev. 2003 Apr 1;17(7):883-95. doi: 10.1101/gad.1063703. Epub 2003 Mar 21. Genes Dev. 2003. PMID: 12654726 Free PMC article.
Collaboration of Brca1 and Chk2 in tumorigenesis.
McPherson JP, Lemmers B, Hirao A, Hakem A, Abraham J, Migon E, Matysiak-Zablocki E, Tamblyn L, Sanchez-Sweatman O, Khokha R, Squire J, Hande MP, Mak TW, Hakem R. McPherson JP, et al. Among authors: hakem a, hakem r. Genes Dev. 2004 May 15;18(10):1144-53. doi: 10.1101/gad.1192704. Epub 2004 May 6. Genes Dev. 2004. PMID: 15131084 Free PMC article.
Involvement of mammalian Mus81 in genome integrity and tumor suppression.
McPherson JP, Lemmers B, Chahwan R, Pamidi A, Migon E, Matysiak-Zablocki E, Moynahan ME, Essers J, Hanada K, Poonepalli A, Sanchez-Sweatman O, Khokha R, Kanaar R, Jasin M, Hande MP, Hakem R. McPherson JP, et al. Among authors: hakem r. Science. 2004 Jun 18;304(5678):1822-6. doi: 10.1126/science.1094557. Science. 2004. PMID: 15205536
Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity.
McPherson JP, Tamblyn L, Elia A, Migon E, Shehabeldin A, Matysiak-Zablocki E, Lemmers B, Salmena L, Hakem A, Fish J, Kassam F, Squire J, Bruneau BG, Hande MP, Hakem R. McPherson JP, et al. Among authors: hakem a, hakem r. EMBO J. 2004 Sep 15;23(18):3677-88. doi: 10.1038/sj.emboj.7600371. Epub 2004 Sep 2. EMBO J. 2004. PMID: 15343267 Free PMC article.
A role for Brca1 in chromosome end maintenance.
McPherson JP, Hande MP, Poonepalli A, Lemmers B, Zablocki E, Migon E, Shehabeldin A, Porras A, Karaskova J, Vukovic B, Squire J, Hakem R. McPherson JP, et al. Among authors: hakem r. Hum Mol Genet. 2006 Mar 15;15(6):831-8. doi: 10.1093/hmg/ddl002. Epub 2006 Jan 30. Hum Mol Genet. 2006. PMID: 16446310
Essential role for caspase-8 in Toll-like receptors and NFkappaB signaling.
Lemmers B, Salmena L, Bidère N, Su H, Matysiak-Zablocki E, Murakami K, Ohashi PS, Jurisicova A, Lenardo M, Hakem R, Hakem A. Lemmers B, et al. Among authors: hakem a, hakem r. J Biol Chem. 2007 Mar 9;282(10):7416-23. doi: 10.1074/jbc.M606721200. Epub 2007 Jan 9. J Biol Chem. 2007. PMID: 17213198 Free article.
113 results