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Targeting FOXM1 in cancer.
Halasi M, Gartel AL. Halasi M, et al. Biochem Pharmacol. 2013 Mar 1;85(5):644-652. doi: 10.1016/j.bcp.2012.10.013. Epub 2012 Oct 24. Biochem Pharmacol. 2013. PMID: 23103567 Review.
Nuclear FOXM1 drives chemoresistance in AML.
Khan I, Halasi M, Zia MF, Gann P, Gaitonde S, Mahmud N, Gartel AL. Khan I, et al. Among authors: halasi m. Leukemia. 2017 Jan;31(1):251-255. doi: 10.1038/leu.2016.270. Epub 2016 Oct 3. Leukemia. 2017. PMID: 27694928 Free article. No abstract available.
P-TEFb inhibitors interfere with activation of p53 by DNA-damaging agents.
Radhakrishnan SK, Bhat UG, Halasi M, Gartel AL. Radhakrishnan SK, et al. Among authors: halasi m. Oncogene. 2008 Feb 21;27(9):1306-9. doi: 10.1038/sj.onc.1210737. Epub 2007 Sep 3. Oncogene. 2008. PMID: 17724473
Combination treatment with bortezomib and thiostrepton is effective against tumor formation in mouse models of DEN/PB-induced liver carcinogenesis.
Wang M, Halasi M, Kabirov K, Banerjee A, Landolfi J, Lyubimov AV, Gartel AL. Wang M, et al. Among authors: halasi m. Cell Cycle. 2012 Sep 15;11(18):3370-2. doi: 10.4161/cc.21290. Epub 2012 Aug 16. Cell Cycle. 2012. PMID: 22894930 Free PMC article.
A novel mode of FoxM1 regulation: positive auto-regulatory loop.
Halasi M, Gartel AL. Halasi M, et al. Cell Cycle. 2009 Jun 15;8(12):1966-7. doi: 10.4161/cc.8.12.8708. Epub 2009 Jun 9. Cell Cycle. 2009. PMID: 19411834
Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells.
Bhat UG, Halasi M, Gartel AL. Bhat UG, et al. Among authors: halasi m. PLoS One. 2009;4(5):e5592. doi: 10.1371/journal.pone.0005592. Epub 2009 May 18. PLoS One. 2009. PMID: 19440351 Free PMC article.
Honokiol is a FOXM1 antagonist.
Halasi M, Hitchinson B, Shah BN, Váraljai R, Khan I, Benevolenskaya EV, Gaponenko V, Arbiser JL, Gartel AL. Halasi M, et al. Cell Death Dis. 2018 Jan 24;9(2):84. doi: 10.1038/s41419-017-0156-7. Cell Death Dis. 2018. PMID: 29367668 Free PMC article.
A Novel Function of Molecular Chaperone HSP70: SUPPRESSION OF ONCOGENIC FOXM1 AFTER PROTEOTOXIC STRESS.
Halasi M, Váraljai R, Benevolenskaya E, Gartel AL. Halasi M, et al. J Biol Chem. 2016 Jan 1;291(1):142-8. doi: 10.1074/jbc.M115.678227. Epub 2015 Nov 11. J Biol Chem. 2016. PMID: 26559972 Free PMC article.
Combination of oxidative stress and FOXM1 inhibitors induces apoptosis in cancer cells and inhibits xenograft tumor growth.
Halasi M, Pandit B, Wang M, Nogueira V, Hay N, Gartel AL. Halasi M, et al. Am J Pathol. 2013 Jul;183(1):257-65. doi: 10.1016/j.ajpath.2013.03.012. Epub 2013 May 10. Am J Pathol. 2013. PMID: 23665201 Free PMC article.
FOX(M1) news--it is cancer.
Halasi M, Gartel AL. Halasi M, et al. Mol Cancer Ther. 2013 Mar;12(3):245-54. doi: 10.1158/1535-7163.MCT-12-0712. Epub 2013 Feb 26. Mol Cancer Ther. 2013. PMID: 23443798 Free PMC article. Review.
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