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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Ørntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, Gorgoulis VG. Bartkova J, et al. Among authors: halazonetis td. Nature. 2006 Nov 30;444(7119):633-7. doi: 10.1038/nature05268. Nature. 2006. PMID: 17136093
Genomic instability--an evolving hallmark of cancer.
Negrini S, Gorgoulis VG, Halazonetis TD. Negrini S, et al. Among authors: halazonetis td. Nat Rev Mol Cell Biol. 2010 Mar;11(3):220-8. doi: 10.1038/nrm2858. Nat Rev Mol Cell Biol. 2010. PMID: 20177397 Review.
TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint.
Cescutti R, Negrini S, Kohzaki M, Halazonetis TD. Cescutti R, et al. Among authors: halazonetis td. EMBO J. 2010 Nov 3;29(21):3723-32. doi: 10.1038/emboj.2010.238. Epub 2010 Sep 24. EMBO J. 2010. PMID: 20871591 Free PMC article.
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.
Nikolaev SI, Rimoldi D, Iseli C, Valsesia A, Robyr D, Gehrig C, Harshman K, Guipponi M, Bukach O, Zoete V, Michielin O, Muehlethaler K, Speiser D, Beckmann JS, Xenarios I, Halazonetis TD, Jongeneel CV, Stevenson BJ, Antonarakis SE. Nikolaev SI, et al. Among authors: halazonetis td. Nat Genet. 2011 Dec 25;44(2):133-9. doi: 10.1038/ng.1026. Nat Genet. 2011. PMID: 22197931
Conservative DNA replication.
Halazonetis TD. Halazonetis TD. Nat Rev Mol Cell Biol. 2014 May;15(5):300. doi: 10.1038/nrm3784. Epub 2014 Mar 26. Nat Rev Mol Cell Biol. 2014. PMID: 24667655 No abstract available.
130 results