Halford SE - Search Results

1

MSI-low, a real phenomenon which varies in frequency among cancer types.

Halford SE, Sawyer EJ, Lambros MB, Gorman P, Macdonald ND, Talbot IC, Foulkes WD, Gillett CE, Barnes DM, Akslen LA, Lee K, Jacobs IJ, Hanby AM, Ganesan TS, Salvesen HB, Bodmer WF, Tomlinson IP, Roylance RR. Halford SE, et al. J Pathol. 2003 Nov;201(3):389-94. doi: 10.1002/path.1453. J Pathol. 2003. PMID: 14595750

2

Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.

Halford SE, Rowan AJ, Lipton L, Sieber OM, Pack K, Thomas HJ, Hodgson SV, Bodmer WF, Tomlinson IP. Halford SE, et al. Am J Pathol. 2003 May;162(5):1545-8. doi: 10.1016/S0002-9440(10)64288-5. Am J Pathol. 2003. PMID: 12707038 Free PMC article.

3

Array-CGH analysis of microsatellite-stable, near-diploid bowel cancers and comparison with other types of colorectal carcinoma.

Jones AM, Douglas EJ, Halford SE, Fiegler H, Gorman PA, Roylance RR, Carter NP, Tomlinson IP. Jones AM, et al. Among authors: halford se. Oncogene. 2005 Jan 6;24(1):118-29. doi: 10.1038/sj.onc.1208194. Oncogene. 2005. PMID: 15531920

4

Does MSI-low exist?

Tomlinson I, Halford S, Aaltonen L, Hawkins N, Ward R. Tomlinson I, et al. J Pathol. 2002 May;197(1):6-13. doi: 10.1002/path.1071. J Pathol. 2002. PMID: 12081205 Review.

5

Most low-level microsatellite instability in colorectal cancers can be explained without an elevated slippage rate.

Graham T, Halford S, Page KM, Tomlinson IP. Graham T, et al. J Pathol. 2008 Jun;215(2):204-10. doi: 10.1002/path.2351. J Pathol. 2008. PMID: 18442191

6

Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait.

Halford S, Sasieni P, Rowan A, Wasan H, Bodmer W, Talbot I, Hawkins N, Ward R, Tomlinson I. Halford S, et al. Cancer Res. 2002 Jan 1;62(1):53-7. Cancer Res. 2002. PMID: 11782358

7

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway.

Woodford-Richens KL, Rowan AJ, Gorman P, Halford S, Bicknell DC, Wasan HS, Roylance RR, Bodmer WF, Tomlinson IP. Woodford-Richens KL, et al. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9719-23. doi: 10.1073/pnas.171321498. Epub 2001 Jul 31. Proc Natl Acad Sci U S A. 2001. PMID: 11481457 Free PMC article.

8

Refining molecular analysis in the pathways of colorectal carcinogenesis.

Rowan A, Halford S, Gaasenbeek M, Kemp Z, Sieber O, Volikos E, Douglas E, Fiegler H, Carter N, Talbot I, Silver A, Tomlinson I. Rowan A, et al. Clin Gastroenterol Hepatol. 2005 Nov;3(11):1115-23. doi: 10.1016/s1542-3565(05)00618-x. Clin Gastroenterol Hepatol. 2005. PMID: 16271343

9

CDX2 mutations do not account for juvenile polyposis or Peutz-Jeghers syndrome and occur infrequently in sporadic colorectal cancers.

Woodford-Richens KL, Halford S, Rowan A, Bevan S, Aaltonen LA, Wasan H, Bicknell D, Bodmer WF, Houlston RS, Tomlinson IP. Woodford-Richens KL, et al. Br J Cancer. 2001 May 18;84(10):1314-6. doi: 10.1054/bjoc.2001.1800. Br J Cancer. 2001. PMID: 11355940 Free PMC article.

10

O(6)-methylguanine methyltransferase in colorectal cancers: detection of mutations, loss of expression, and weak association with G:C>A:T transitions.

Halford S, Rowan A, Sawyer E, Talbot I, Tomlinson I. Halford S, et al. Gut. 2005 Jun;54(6):797-802. doi: 10.1136/gut.2004.059535. Gut. 2005. PMID: 15888787 Free PMC article.

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