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Purification of recombinant Rho/Rac/G25K from Escherichia coli.
Self AJ, Hall A. Self AJ, et al. Among authors: hall a. Methods Enzymol. 1995;256:3-10. doi: 10.1016/0076-6879(95)56003-3. Methods Enzymol. 1995. PMID: 7476445 No abstract available.
Plexin-induced collapse assay in COS cells.
Turner LJ, Hall A. Turner LJ, et al. Among authors: hall a. Methods Enzymol. 2006;406:665-76. doi: 10.1016/S0076-6879(06)06052-6. Methods Enzymol. 2006. PMID: 16472696
Semaphorins are a family of growth cone guidance molecules. When associated with their receptors and coreceptors, plexins and neuropilins, they act as chemorepellents for an extensive range of neuronal populations. ...Recently, a heterologous, highly tractable assay …
Semaphorins are a family of growth cone guidance molecules. When associated with their receptors and coreceptors, plexins and neuropi …
Cell migration: Rho GTPases lead the way.
Raftopoulou M, Hall A. Raftopoulou M, et al. Among authors: hall a. Dev Biol. 2004 Jan 1;265(1):23-32. doi: 10.1016/j.ydbio.2003.06.003. Dev Biol. 2004. PMID: 14697350 Review.
Rho GTPases control signal transduction pathways that link cell surface receptors to a variety of intracellular responses. They are best known as regulators of the actin cytoskeleton, but in addition they control cell polarity, gene expression, microtubule dynamics and ves …
Rho GTPases control signal transduction pathways that link cell surface receptors to a variety of intracellular responses. They are b …
Rho GTPases: biochemistry and biology.
Jaffe AB, Hall A. Jaffe AB, et al. Among authors: hall a. Annu Rev Cell Dev Biol. 2005;21:247-69. doi: 10.1146/annurev.cellbio.21.020604.150721. Annu Rev Cell Dev Biol. 2005. PMID: 16212495 Review.
Through a series of complex biochemical networks, these highly conserved molecular switches control some of the most fundamental processes of cell biology common to all eukaryotes, including morphogenesis, polarity, movement, and cell division. In the first part of this re …
Through a series of complex biochemical networks, these highly conserved molecular switches control some of the most fundamental proc …
Snails, Swiss, and serum: the solution for Rac 'n' Rho.
Ridley AJ, Hall A. Ridley AJ, et al. Among authors: hall a. Cell. 2004 Jan 23;116(2 Suppl):S23-5, 2 p following S25. doi: 10.1016/s0092-8674(04)00048-0. Cell. 2004. PMID: 15055577 No abstract available.
The activity of the plexin-A1 receptor is regulated by Rac.
Turner LJ, Nicholls S, Hall A. Turner LJ, et al. Among authors: hall a. J Biol Chem. 2004 Aug 6;279(32):33199-205. doi: 10.1074/jbc.M402943200. Epub 2004 Jun 8. J Biol Chem. 2004. PMID: 15187088
Sema3A/Plexin-A1-induced growth cone collapse, for example, requires Rac activity, which is a surprising result given that this GTPase is usually associated with membrane protrusions. ...However, collapse induced by a constitutively activated version of Plexin-A1 do …
Sema3A/Plexin-A1-induced growth cone collapse, for example, requires Rac activity, which is a surprising result given that this GTPas …
Association of CNK1 with Rho guanine nucleotide exchange factors controls signaling specificity downstream of Rho.
Jaffe AB, Hall A, Schmidt A. Jaffe AB, et al. Among authors: hall a. Curr Biol. 2005 Mar 8;15(5):405-12. doi: 10.1016/j.cub.2004.12.082. Curr Biol. 2005. PMID: 15753034
BACKGROUND: Rho is a small GTPase that controls signal transduction pathways in response to a large number of extracellular stimuli. With over 15 potential Rho target proteins identified to date, however, it is not clear how distinct signaling outputs can be generat …
BACKGROUND: Rho is a small GTPase that controls signal transduction pathways in response to a large number of extracellular st …
Cell biology. Smurfing at the leading edge.
Jaffe AB, Hall A. Jaffe AB, et al. Among authors: hall a. Science. 2003 Dec 5;302(5651):1690-1. doi: 10.1126/science.1092874. Science. 2003. PMID: 14657480 No abstract available.
Rho GTPases in cell biology.
Etienne-Manneville S, Hall A. Etienne-Manneville S, et al. Among authors: hall a. Nature. 2002 Dec 12;420(6916):629-35. doi: 10.1038/nature01148. Nature. 2002. PMID: 12478284 Review.
Underlying this biological complexity is a simple biochemical idea, namely that by switching on a single GTPase, several distinct signalling pathways can be coordinately activated. With spatial and temporal activation of multiple switches factored in, it is not surp …
Underlying this biological complexity is a simple biochemical idea, namely that by switching on a single GTPase, several disti …
Rac regulates endothelial morphogenesis and capillary assembly.
Connolly JO, Simpson N, Hewlett L, Hall A. Connolly JO, et al. Among authors: hall a. Mol Biol Cell. 2002 Jul;13(7):2474-85. doi: 10.1091/mbc.e02-01-0006. Mol Biol Cell. 2002. PMID: 12134084 Free PMC article.
The addition of matrix first induces changes in cell morphology characterized by the formation of dynamic cellular protrusions and the assembly of discrete aggregates or cords of aligned cells resembling primitive capillary-like structures, but without a recognizable lumen …
The addition of matrix first induces changes in cell morphology characterized by the formation of dynamic cellular protrusions and the assem …
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