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Rapamycin passes the torch: a new generation of mTOR inhibitors.
Benjamin D, Colombi M, Moroni C, Hall MN. Benjamin D, et al. Among authors: hall mn. Nat Rev Drug Discov. 2011 Oct 31;10(11):868-80. doi: 10.1038/nrd3531. Nat Rev Drug Discov. 2011. PMID: 22037041 Review.
The TOR-controlled transcription activators GLN3, RTG1, and RTG3 are regulated in response to intracellular levels of glutamine.
Crespo JL, Powers T, Fowler B, Hall MN. Crespo JL, et al. Among authors: hall mn. Proc Natl Acad Sci U S A. 2002 May 14;99(10):6784-9. doi: 10.1073/pnas.102687599. Epub 2002 May 7. Proc Natl Acad Sci U S A. 2002. PMID: 11997479 Free PMC article.
Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.
Loewith R, Jacinto E, Wullschleger S, Lorberg A, Crespo JL, Bonenfant D, Oppliger W, Jenoe P, Hall MN. Loewith R, et al. Among authors: hall mn. Mol Cell. 2002 Sep;10(3):457-68. doi: 10.1016/s1097-2765(02)00636-6. Mol Cell. 2002. PMID: 12408816
Elucidating TOR signaling and rapamycin action: lessons from Saccharomyces cerevisiae.
Crespo JL, Hall MN. Crespo JL, et al. Among authors: hall mn. Microbiol Mol Biol Rev. 2002 Dec;66(4):579-91, table of contents. doi: 10.1128/mmbr.66.4.579-591.2002. Microbiol Mol Biol Rev. 2002. PMID: 12456783 Free PMC article. Review.
Tor signalling in bugs, brain and brawn.
Jacinto E, Hall MN. Jacinto E, et al. Among authors: hall mn. Nat Rev Mol Cell Biol. 2003 Feb;4(2):117-26. doi: 10.1038/nrm1018. Nat Rev Mol Cell Biol. 2003. PMID: 12563289 Review.
Activation of the RAS/cyclic AMP pathway suppresses a TOR deficiency in yeast.
Schmelzle T, Beck T, Martin DE, Hall MN. Schmelzle T, et al. Among authors: hall mn. Mol Cell Biol. 2004 Jan;24(1):338-51. doi: 10.1128/mcb.24.1.338-351.2004. Mol Cell Biol. 2004. PMID: 14673167 Free PMC article.
NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae.
Crespo JL, Helliwell SB, Wiederkehr C, Demougin P, Fowler B, Primig M, Hall MN. Crespo JL, et al. Among authors: hall mn. J Biol Chem. 2004 Sep 3;279(36):37512-7. doi: 10.1074/jbc.M407372200. Epub 2004 Jul 9. J Biol Chem. 2004. PMID: 15247235
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Jacinto E, Loewith R, Schmidt A, Lin S, Rüegg MA, Hall A, Hall MN. Jacinto E, et al. Among authors: hall a, hall mn. Nat Cell Biol. 2004 Nov;6(11):1122-8. doi: 10.1038/ncb1183. Epub 2004 Oct 3. Nat Cell Biol. 2004. PMID: 15467718
TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1.
Martin DE, Soulard A, Hall MN. Martin DE, et al. Among authors: hall mn. Cell. 2004 Dec 29;119(7):969-79. doi: 10.1016/j.cell.2004.11.047. Cell. 2004. PMID: 15620355
The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability.
Dames SA, Mulet JM, Rathgeb-Szabo K, Hall MN, Grzesiek S. Dames SA, et al. Among authors: hall mn. J Biol Chem. 2005 May 27;280(21):20558-64. doi: 10.1074/jbc.M501116200. Epub 2005 Mar 16. J Biol Chem. 2005. PMID: 15772072
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