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The p75 neurotrophin receptor is a central regulator of glioma invasion.
Johnston AL, Lun X, Rahn JJ, Liacini A, Wang L, Hamilton MG, Parney IF, Hempstead BL, Robbins SM, Forsyth PA, Senger DL. Johnston AL, et al. Among authors: Hamilton MG. Version 2. PLoS Biol. 2007 Aug;5(8):e212. doi: 10.1371/journal.pbio.0050212. PLoS Biol. 2007. PMID: 17696644 Free PMC article.
Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates.
Yang WQ, Lun X, Palmer CA, Wilcox ME, Muzik H, Shi ZQ, Dyck R, Coffey M, Thompson B, Hamilton M, Nishikawa SG, Brasher PM, Fonseca K, George D, Rewcastle NB, Johnston RN, Stewart D, Lee PW, Senger DL, Forsyth PA. Yang WQ, et al. Among authors: Hamilton M. Clin Cancer Res. 2004 Dec 15;10(24):8561-76. doi: 10.1158/1078-0432.CCR-04-0940. Clin Cancer Res. 2004. PMID: 15623640
Effects of intravenously administered recombinant vesicular stomatitis virus (VSV(deltaM51)) on multifocal and invasive gliomas.
Lun X, Senger DL, Alain T, Oprea A, Parato K, Stojdl D, Lichty B, Power A, Johnston RN, Hamilton M, Parney I, Bell JC, Forsyth PA. Lun X, et al. Among authors: Hamilton M. J Natl Cancer Inst. 2006 Nov 1;98(21):1546-57. doi: 10.1093/jnci/djj413. J Natl Cancer Inst. 2006. PMID: 17077357
A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas.
Forsyth P, Roldán G, George D, Wallace C, Palmer CA, Morris D, Cairncross G, Matthews MV, Markert J, Gillespie Y, Coffey M, Thompson B, Hamilton M. Forsyth P, et al. Among authors: Hamilton M. Mol Ther. 2008 Mar;16(3):627-32. doi: 10.1038/sj.mt.6300403. Epub 2008 Feb 5. Mol Ther. 2008. PMID: 18253152 Clinical Trial.
Treating brain tumor-initiating cells using a combination of myxoma virus and rapamycin.
Zemp FJ, Lun X, McKenzie BA, Zhou H, Maxwell L, Sun B, Kelly JJ, Stechishin O, Luchman A, Weiss S, Cairncross JG, Hamilton MG, Rabinovich BA, Rahman MM, Mohamed MR, Smallwood S, Senger DL, Bell J, McFadden G, Forsyth PA. Zemp FJ, et al. Among authors: Hamilton MG. Neuro Oncol. 2013 Jul;15(7):904-20. doi: 10.1093/neuonc/not035. Epub 2013 Apr 12. Neuro Oncol. 2013. PMID: 23585629 Free PMC article.
Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells.
Sarkar S, Döring A, Zemp FJ, Silva C, Lun X, Wang X, Kelly J, Hader W, Hamilton M, Mercier P, Dunn JF, Kinniburgh D, van Rooijen N, Robbins S, Forsyth P, Cairncross G, Weiss S, Yong VW. Sarkar S, et al. Among authors: Hamilton M. Nat Neurosci. 2014 Jan;17(1):46-55. doi: 10.1038/nn.3597. Epub 2013 Dec 8. Nat Neurosci. 2014. PMID: 24316889
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