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Page 1
Sepsis-trained macrophages promote antitumoral tissue-resident T cells.
Broquet A, Gourain V, Goronflot T, Le Mabecque V, Sinha D, Ashayeripanah M, Jacqueline C, Martin P, Davieau M, Boutin L, Poulain C, Martin FP, Fourgeux C, Petrier M, Cannevet M, Leclercq T, Guillonneau M, Chaumette T, Laurent T, Harly C, Scotet E, Legentil L, Ferrières V, Corgnac S, Mami-Chouaib F, Mosnier JF, Mauduit N, McWilliam HEG, Villadangos JA, Gourraud PA, Asehnoune K, Poschmann J, Roquilly A. Broquet A, et al. Among authors: mcwilliam heg. Nat Immunol. 2024 May;25(5):802-819. doi: 10.1038/s41590-024-01819-8. Epub 2024 Apr 29. Nat Immunol. 2024. PMID: 38684922 Free article.
Macrophage MR1 antigen presentation promotes MAIT cell immunity and lung microbiota modulation.
Deng J, Yan Y, Zhang X, Walsh CJ, Montassier E, Sinha D, Wang H, Mousavizadeh A, Ashayeripanah M, Mak JYW, Koay HF, Poch T, Alexandre YO, Mueller SN, Vasanthakumar A, Stinear TP, Jameson VJ, Perez-Gonzalez A, Kingham J, Phan TG, Potemkin N, Dryburgh L, Schroeder J, Fairlie DP, Mackay LK, Chen Z, Cook L, Hachani A, Corbett AJ, Roquilly A, Villadangos JA, McWilliam HEG. Deng J, et al. Among authors: mcwilliam heg. Science. 2026 Jan 15;391(6782):eadr6322. doi: 10.1126/science.adr6322. Epub 2026 Jan 15. Science. 2026. PMID: 41343603
Alveolar macrophages are epigenetically altered after inflammation, leading to long-term lung immunoparalysis.
Roquilly A, Jacqueline C, Davieau M, Mollé A, Sadek A, Fourgeux C, Rooze P, Broquet A, Misme-Aucouturier B, Chaumette T, Vourc'h M, Cinotti R, Marec N, Gauttier V, McWilliam HEG, Altare F, Poschmann J, Villadangos JA, Asehnoune K. Roquilly A, et al. Among authors: mcwilliam heg. Nat Immunol. 2020 Jun;21(6):636-648. doi: 10.1038/s41590-020-0673-x. Epub 2020 May 18. Nat Immunol. 2020. PMID: 32424365
Author Correction: Sepsis-trained macrophages promote antitumoral tissue-resident T cells.
Broquet A, Gourain V, Goronflot T, Le Mabecque V, Sinha D, Ashayeripanah M, Jacqueline C, Martin P, Davieau M, Boutin L, Poulain C, Martin FP, Fourgeux C, Petrier M, Cannevet M, Leclercq T, Guillonneau M, Chaumette T, Laurent T, Harly C, Scotet E, Legentil L, Ferrières V, Corgnac S, Mami-Chouaib F, Mosnier JF, Mauduit N, McWilliam HEG, Villadangos JA, Gourraud PA, Asehnoune K, Poschmann J, Roquilly A. Broquet A, et al. Among authors: mcwilliam heg. Nat Immunol. 2024 Nov;25(11):2167. doi: 10.1038/s41590-024-02000-x. Nat Immunol. 2024. PMID: 39375552 No abstract available.
The antigen-presenting molecule MR1 binds host-generated riboflavin catabolites.
Abdelaal MR, Deng J, McInerney MP, Ito E, Purcell AW, Yamasaki S, Villadangos JA, McWilliam HEG, Gherardin NA, Rossjohn J, Awad W. Abdelaal MR, et al. Among authors: mcwilliam heg. J Exp Med. 2026 Feb 2;223(2):e20250711. doi: 10.1084/jem.20250711. Epub 2025 Nov 26. J Exp Med. 2026. PMID: 41295949 Free PMC article.
MR1 presentation of vitamin B-based metabolite ligands.
McWilliam HE, Birkinshaw RW, Villadangos JA, McCluskey J, Rossjohn J. McWilliam HE, et al. Curr Opin Immunol. 2015 Jun;34:28-34. doi: 10.1016/j.coi.2014.12.004. Epub 2015 Jan 17. Curr Opin Immunol. 2015. PMID: 25603223 Review.
The antigen presenting molecule MR1 binds riboflavin catabolites.
Abdelaal MR, Deng J, McInerney MP, Ito E, Purcell AW, Yamasaki S, Villadangos J, McWilliam HEG, Gherardin NA, Rossjohn J, Awad W. Abdelaal MR, et al. Among authors: mcwilliam heg. bioRxiv [Preprint]. 2025 Jul 20:2025.07.20.665728. doi: 10.1101/2025.07.20.665728. bioRxiv. 2025. Update in: J Exp Med. 2026 Feb 2;223(2):e20250711. doi: 10.1084/jem.20250711. PMID: 40791435 Free PMC article. Updated. Preprint.
49 results