Hammacher A - Search Results

1

Interleukin-6: structure-function relationships.

Simpson RJ, Hammacher A, Smith DK, Matthews JM, Ward LD. Simpson RJ, et al. Among authors: hammacher a. Protein Sci. 1997 May;6(5):929-55. doi: 10.1002/pro.5560060501. Protein Sci. 1997. PMID: 9144766 Free PMC article. Review.

2

Structure-function analysis of human IL-6: identification of two distinct regions that are important for receptor binding.

Hammacher A, Ward LD, Weinstock J, Treutlein H, Yasukawa K, Simpson RJ. Hammacher A, et al. Protein Sci. 1994 Dec;3(12):2280-93. doi: 10.1002/pro.5560031213. Protein Sci. 1994. PMID: 7538847 Free PMC article.

3

Structural and biological characterization of murine-human interleukin-6 chimeras.

Hammacher A, Ward LD, Weinstock J, Simpson RJ. Hammacher A, et al. Ann N Y Acad Sci. 1995 Jul 21;762:422-3. doi: 10.1111/j.1749-6632.1995.tb32354.x. Ann N Y Acad Sci. 1995. PMID: 7668546 No abstract available.

4

High affinity interleukin-6 receptor is a hexameric complex consisting of two molecules each of interleukin-6, interleukin-6 receptor, and gp-130.

Ward LD, Howlett GJ, Discolo G, Yasukawa K, Hammacher A, Moritz RL, Simpson RJ. Ward LD, et al. Among authors: hammacher a. J Biol Chem. 1994 Sep 16;269(37):23286-9. J Biol Chem. 1994. PMID: 8083235 Free article.

5

Role of the C-terminus in the activity, conformation, and stability of interleukin-6.

Ward LD, Hammacher A, Zhang JG, Weinstock J, Yasukawa K, Morton CJ, Norton RS, Simpson RJ. Ward LD, et al. Among authors: hammacher a. Protein Sci. 1993 Sep;2(9):1472-81. doi: 10.1002/pro.5560020911. Protein Sci. 1993. PMID: 8401231 Free PMC article.

6

Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex.

Ward LD, Hammacher A, Howlett GJ, Matthews JM, Fabri L, Moritz RL, Nice EC, Weinstock J, Simpson RJ. Ward LD, et al. Among authors: hammacher a. J Biol Chem. 1996 Aug 16;271(33):20138-44. doi: 10.1074/jbc.271.33.20138. J Biol Chem. 1996. PMID: 8702737 Free article.

7

Roles of histidine 31 and tryptophan 34 in the structure, self-association, and folding of murine interleukin-6.

Matthews JM, Ward LD, Hammacher A, Norton RS, Simpson RJ. Matthews JM, et al. Among authors: hammacher a. Biochemistry. 1997 May 20;36(20):6187-96. doi: 10.1021/bi962939w. Biochemistry. 1997. PMID: 9166791

8

NMR studies of the solution properties of recombinant murine interleukin-6.

Morton CJ, Bai H, Zhang JG, Hammacher A, Norton RS, Simpson RJ, Mabbutt BC. Morton CJ, et al. Among authors: hammacher a. Biochim Biophys Acta. 1995 Jun 12;1249(2):189-203. doi: 10.1016/0167-4838(95)00023-n. Biochim Biophys Acta. 1995. PMID: 7599173

9

Stoichiometry of the interleukin-6 high affinity receptor complex.

Ward LD, Howlett GJ, Hammacher A, Moritz RL, Simpson RJ. Ward LD, et al. Among authors: hammacher a. Ann N Y Acad Sci. 1995 Jul 21;762:471-3. doi: 10.1111/j.1749-6632.1995.tb32371.x. Ann N Y Acad Sci. 1995. PMID: 7668561 No abstract available.

10

Use of a biosensor with surface plasmon resonance detection for the determination of binding constants: measurement of interleukin-6 binding to the soluble interleukin-6 receptor.

Ward LD, Howlett GJ, Hammacher A, Weinstock J, Yasukawa K, Simpson RJ, Winzor DJ. Ward LD, et al. Among authors: hammacher a. Biochemistry. 1995 Mar 7;34(9):2901-7. doi: 10.1021/bi00009a021. Biochemistry. 1995. PMID: 7893704

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