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HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.
Neubert P, Weichselbaum A, Reitinger C, Schatz V, Schröder A, Ferdinand JR, Simon M, Bär AL, Brochhausen C, Gerlach RG, Tomiuk S, Hammer K, Wagner S, van Zandbergen G, Binger KJ, Müller DN, Kitada K, Clatworthy MR, Kurts C, Titze J, Abdullah Z, Jantsch J. Neubert P, et al. Among authors: hammer k. Autophagy. 2019 Nov;15(11):1899-1916. doi: 10.1080/15548627.2019.1596483. Epub 2019 Apr 14. Autophagy. 2019. PMID: 30982460 Free PMC article.
NCX1 represents an ionic Na+ sensing mechanism in macrophages.
Neubert P, Homann A, Wendelborn D, Bär AL, Krampert L, Trum M, Schröder A, Ebner S, Weichselbaum A, Schatz V, Linz P, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Geisberger S, Kunzelmann K, Hammer K, Binger KJ, Titze J, Müller DN, Kolanus W, Schultze JL, Wagner S, Jantsch J. Neubert P, et al. Among authors: hammer k. PLoS Biol. 2020 Jun 22;18(6):e3000722. doi: 10.1371/journal.pbio.3000722. eCollection 2020 Jun. PLoS Biol. 2020. PMID: 32569301 Free PMC article.
Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes.
Mustroph J, Wagemann O, Lücht CM, Trum M, Hammer KP, Sag CM, Lebek S, Tarnowski D, Reinders J, Perbellini F, Terracciano C, Schmid C, Schopka S, Hilker M, Zausig Y, Pabel S, Sossalla ST, Schweda F, Maier LS, Wagner S. Mustroph J, et al. ESC Heart Fail. 2018 Aug;5(4):642-648. doi: 10.1002/ehf2.12336. ESC Heart Fail. 2018. PMID: 30117720 Free PMC article.
Long-term effects of empagliflozin on excitation-contraction-coupling in human induced pluripotent stem cell cardiomyocytes.
Pabel S, Reetz F, Dybkova N, Shomroni O, Salinas G, Mustroph J, Hammer KP, Hasenfuss G, Hamdani N, Maier LS, Streckfuss-Bömeke K, Sossalla S. Pabel S, et al. Among authors: hammer kp. J Mol Med (Berl). 2020 Dec;98(12):1689-1700. doi: 10.1007/s00109-020-01989-6. Epub 2020 Oct 9. J Mol Med (Berl). 2020. PMID: 33034709 Free PMC article.
389 results