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Mutation-Derived Tumor Antigens: Novel Targets in Cancer Immunotherapy.
Finnigan JP Jr, Rubinsteyn A, Hammerbacher J, Bhardwaj N. Finnigan JP Jr, et al. Oncology (Williston Park). 2015 Dec;29(12):970-2, 974-5. Oncology (Williston Park). 2015. PMID: 26676902 Review. No abstract available.
Informatics for cancer immunotherapy.
Hammerbacher J, Snyder A. Hammerbacher J, et al. Ann Oncol. 2017 Dec 1;28(suppl_12):xii56-xii73. doi: 10.1093/annonc/mdx682. Ann Oncol. 2017. PMID: 29253114 Free PMC article. Review.
Computational Pipeline for the PGV-001 Neoantigen Vaccine Trial.
Rubinsteyn A, Kodysh J, Hodes I, Mondet S, Aksoy BA, Finnigan JP, Bhardwaj N, Hammerbacher J. Rubinsteyn A, et al. Among authors: hammerbacher j. Front Immunol. 2018 Jan 18;8:1807. doi: 10.3389/fimmu.2017.01807. eCollection 2017. Front Immunol. 2018. PMID: 29403468 Free PMC article.
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.
Hellmann MD, Nathanson T, Rizvi H, Creelan BC, Sanchez-Vega F, Ahuja A, Ni A, Novik JB, Mangarin LMB, Abu-Akeel M, Liu C, Sauter JL, Rekhtman N, Chang E, Callahan MK, Chaft JE, Voss MH, Tenet M, Li XM, Covello K, Renninger A, Vitazka P, Geese WJ, Borghaei H, Rudin CM, Antonia SJ, Swanton C, Hammerbacher J, Merghoub T, McGranahan N, Snyder A, Wolchok JD. Hellmann MD, et al. Among authors: hammerbacher j. Cancer Cell. 2018 May 14;33(5):843-852.e4. doi: 10.1016/j.ccell.2018.03.018. Epub 2018 Apr 12. Cancer Cell. 2018. PMID: 29657128 Free PMC article.
Chemotherapy weakly contributes to predicted neoantigen expression in ovarian cancer.
O'Donnell T, Christie EL, Ahuja A, Buros J, Aksoy BA, Bowtell DDL, Snyder A, Hammerbacher J. O'Donnell T, et al. BMC Cancer. 2018 Jan 22;18(1):87. doi: 10.1186/s12885-017-3825-0. BMC Cancer. 2018. PMID: 29357823 Free PMC article.
Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade.
Nathanson T, Ahuja A, Rubinsteyn A, Aksoy BA, Hellmann MD, Miao D, Van Allen E, Merghoub T, Wolchok JD, Snyder A, Hammerbacher J. Nathanson T, et al. Cancer Immunol Res. 2017 Jan;5(1):84-91. doi: 10.1158/2326-6066.CIR-16-0019. Epub 2016 Dec 12. Cancer Immunol Res. 2017. PMID: 27956380 Free PMC article.
Contribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: An exploratory multi-omic analysis.
Snyder A, Nathanson T, Funt SA, Ahuja A, Buros Novik J, Hellmann MD, Chang E, Aksoy BA, Al-Ahmadie H, Yusko E, Vignali M, Benzeno S, Boyd M, Moran M, Iyer G, Robins HS, Mardis ER, Merghoub T, Hammerbacher J, Rosenberg JE, Bajorin DF. Snyder A, et al. PLoS Med. 2017 May 26;14(5):e1002309. doi: 10.1371/journal.pmed.1002309. eCollection 2017 May. PLoS Med. 2017. PMID: 28552987 Free PMC article. Clinical Trial.
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy.
Yamamoto TN, Lee PH, Vodnala SK, Gurusamy D, Kishton RJ, Yu Z, Eidizadeh A, Eil R, Fioravanti J, Gattinoni L, Kochenderfer JN, Fry TJ, Aksoy BA, Hammerbacher JE, Cruz AC, Siegel RM, Restifo NP, Klebanoff CA. Yamamoto TN, et al. Among authors: hammerbacher je. J Clin Invest. 2019 Feb 25;129(4):1551-1565. doi: 10.1172/JCI121491. eCollection 2019 Feb 25. J Clin Invest. 2019. PMID: 30694219 Free PMC article.
Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer.
Olcina MM, Balanis NG, Kim RK, Aksoy BA, Kodysh J, Thompson MJ, Hammerbacher J, Graeber TG, Giaccia AJ. Olcina MM, et al. Among authors: hammerbacher j. Cell Rep. 2018 Dec 26;25(13):3721-3732.e6. doi: 10.1016/j.celrep.2018.11.093. Cell Rep. 2018. PMID: 30590044 Free PMC article.
How Will Big Data Improve Clinical and Basic Research in Radiation Therapy?
Rosenstein BS, Capala J, Efstathiou JA, Hammerbacher J, Kerns SL, Kong FS, Ostrer H, Prior FW, Vikram B, Wong J, Xiao Y. Rosenstein BS, et al. Int J Radiat Oncol Biol Phys. 2016 Jul 1;95(3):895-904. doi: 10.1016/j.ijrobp.2015.11.009. Epub 2015 Nov 11. Int J Radiat Oncol Biol Phys. 2016. PMID: 26797542 Free PMC article.
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