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53 results

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Page 1
Optimization of Orally Bioavailable Antileishmanial 2,4,5-Trisubstituted Benzamides.
Kim HS, Ortiz D, Kadayat TM, Fargo CM, Hammill JT, Chen Y, Rice AL, Begley KL, Shoeran G, Pistel W, Yates PA, Sanchez MA, Landfear SM, Guy RK. Kim HS, et al. Among authors: hammill jt. J Med Chem. 2023 Jun 8;66(11):7374-7386. doi: 10.1021/acs.jmedchem.3c00056. Epub 2023 May 22. J Med Chem. 2023. PMID: 37216489 Free PMC article.
Combining SJ733, an oral ATP4 inhibitor of Plasmodium falciparum, with the pharmacokinetic enhancer cobicistat: An innovative approach in antimalarial drug development.
Gaur AH, Panetta JC, Smith AM, Dallas RH, Freeman BB 3rd, Stewart TB, Tang L, John E, Branum KC, Patel ND, Ost S, Heine RN, Richardson JL, Hammill JT, Bebrevska L, Gusovsky F, Maki N, Yanagi T, Flynn PM, McCarthy JS, Chalon S, Guy RK. Gaur AH, et al. Among authors: hammill jt. EBioMedicine. 2022 Jun;80:104065. doi: 10.1016/j.ebiom.2022.104065. Epub 2022 May 19. EBioMedicine. 2022. PMID: 35598441 Free PMC article. Clinical Trial.
Metformin-induced reductions in tumor growth involves modulation of the gut microbiome.
Broadfield LA, Saigal A, Szamosi JC, Hammill JA, Bezverbnaya K, Wang D, Gautam J, Tsakiridis EE, Di Pastena F, McNicol J, Wu J, Syed S, Lally JSV, Raphenya AR, Blouin MJ, Pollak M, Sacconi A, Blandino G, McArthur AG, Schertzer JD, Surette MG, Collins SM, Bramson JL, Muti P, Tsakiridis T, Steinberg GR. Broadfield LA, et al. Among authors: hammill ja. Mol Metab. 2022 Jul;61:101498. doi: 10.1016/j.molmet.2022.101498. Epub 2022 Apr 20. Mol Metab. 2022. PMID: 35452877 Free PMC article.
Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents.
Hammill JT, Sviripa VM, Kril LM, Ortiz D, Fargo CM, Kim HS, Chen Y, Rector J, Rice AL, Domagalska MA, Begley KL, Liu C, Rangnekar VM, Dujardin JC, Watt DS, Landfear SM, Guy RK. Hammill JT, et al. J Med Chem. 2021 Aug 26;64(16):12152-12162. doi: 10.1021/acs.jmedchem.1c00813. Epub 2021 Aug 6. J Med Chem. 2021. PMID: 34355566 Free PMC article.
Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors.
Portillo AL, Hogg R, Poznanski SM, Rojas EA, Cashell NJ, Hammill JA, Chew MV, Shenouda MM, Ritchie TM, Cao QT, Hirota JA, Dhesy-Thind S, Bramson JL, Ashkar AA. Portillo AL, et al. Among authors: hammill ja. iScience. 2021 May 24;24(6):102619. doi: 10.1016/j.isci.2021.102619. eCollection 2021 Jun 25. iScience. 2021. PMID: 34159300 Free PMC article.
53 results