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Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents.
Hammill JT, Sviripa VM, Kril LM, Ortiz D, Fargo CM, Kim HS, Chen Y, Rector J, Rice AL, Domagalska MA, Begley KL, Liu C, Rangnekar VM, Dujardin JC, Watt DS, Landfear SM, Guy RK. Hammill JT, et al. J Med Chem. 2021 Aug 26;64(16):12152-12162. doi: 10.1021/acs.jmedchem.1c00813. Epub 2021 Aug 6. J Med Chem. 2021. PMID: 34355566 Free PMC article.
Antimalarial activity of 2,6-dibenzylidenecyclohexanone derivatives.
Eagon S, Hammill JT, Fitzsimmons K, Sienko N, Nguyen B, Law J, Manjunath A, Wilkinson SP, Thompson K, Glidden JE, Rice AL, Falade MO, Kimball JJ, DiBernardo C, Guy RK. Eagon S, et al. Among authors: hammill jt. Bioorg Med Chem Lett. 2021 Sep 1;47:128216. doi: 10.1016/j.bmcl.2021.128216. Epub 2021 Jun 19. Bioorg Med Chem Lett. 2021. PMID: 34157390 Free article.
Synthesis and Structure-Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines.
Eagon S, Hammill JT, Sigal M, Ahn KJ, Tryhorn JE, Koch G, Belanger B, Chaplan CA, Loop L, Kashtanova AS, Yniguez K, Lazaro H, Wilkinson SP, Rice AL, Falade MO, Takahashi R, Kim K, Cheung A, DiBernardo C, Kimball JJ, Winzeler EA, Eribez K, Mittal N, Gamo FJ, Crespo B, Churchyard A, García-Barbazán I, Baum J, Anderson MO, Laleu B, Guy RK. Eagon S, et al. Among authors: hammill jt. J Med Chem. 2020 Oct 22;63(20):11902-11919. doi: 10.1021/acs.jmedchem.0c01152. Epub 2020 Oct 1. J Med Chem. 2020. PMID: 32945666
Antimalarial activity of tetrahydro-β-carbolines targeting the ATP binding pocket of the Plasmodium falciparum heat shock 90 protein.
Eagon S, Hammill JT, Bach J, Everson N, Sisley TA, Walls MJ, Durham S, Pillai DR, Falade MO, Rice AL, Kimball JJ, Lazaro H, DiBernardo C, Kiplin Guy R. Eagon S, et al. Among authors: hammill jt. Bioorg Med Chem Lett. 2020 Nov 1;30(21):127502. doi: 10.1016/j.bmcl.2020.127502. Epub 2020 Aug 18. Bioorg Med Chem Lett. 2020. PMID: 32822760 Free article.
21 results