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Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation.
Samadder P, Suchánková T, Hylse O, Khirsariya P, Nikulenkov F, Drápela S, Straková N, Vaňhara P, Vašíčková K, Kolářová H, Binó L, Bittová M, Ovesná P, Kollár P, Fedr R, Ešner M, Jaroš J, Hampl A, Krejčí L, Paruch K, Souček K. Samadder P, et al. Among authors: hampl a. Mol Cancer Ther. 2017 Sep;16(9):1831-1842. doi: 10.1158/1535-7163.MCT-17-0018. Epub 2017 Jun 15. Mol Cancer Ther. 2017. PMID: 28619751
Lineage specific composition of cyclin D-CDK4/CDK6-p27 complexes reveals distinct functions of CDK4, CDK6 and individual D-type cyclins in differentiating cells of embryonic origin.
Bryja V, Pacherník J, Vondráček J, Souček K, Čajánek L, Horvath V, Holubcová Z, Dvořák P, Hampl A. Bryja V, et al. Among authors: hampl a. Cell Prolif. 2008 Dec;41(6):875-893. doi: 10.1111/j.1365-2184.2008.00556.x. Cell Prolif. 2008. PMID: 19040567 Free PMC article.
155 results