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ER-associated degradation in protein quality control and cellular regulation.
Hampton RY. Hampton RY. Curr Opin Cell Biol. 2002 Aug;14(4):476-82. doi: 10.1016/s0955-0674(02)00358-7. Curr Opin Cell Biol. 2002. PMID: 12383799 Review.
Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast.
Hampton RY, Rine J. Hampton RY, et al. J Cell Biol. 1994 Apr;125(2):299-312. doi: 10.1083/jcb.125.2.299. J Cell Biol. 1994. PMID: 8163547 Free PMC article.
In vivo examination of membrane protein localization and degradation with green fluorescent protein.
Hampton RY, Koning A, Wright R, Rine J. Hampton RY, et al. Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):828-33. doi: 10.1073/pnas.93.2.828. Proc Natl Acad Sci U S A. 1996. PMID: 8570643 Free PMC article.
The biology of HMG-CoA reductase: the pros of contra-regulation.
Hampton R, Dimster-Denk D, Rine J. Hampton R, et al. Trends Biochem Sci. 1996 Apr;21(4):140-5. Trends Biochem Sci. 1996. PMID: 8701471 Review.
Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein.
Hampton RY, Gardner RG, Rine J. Hampton RY, et al. Mol Biol Cell. 1996 Dec;7(12):2029-44. doi: 10.1091/mbc.7.12.2029. Mol Biol Cell. 1996. PMID: 8970163 Free PMC article.
Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase.
Hampton RY, Bhakta H. Hampton RY, et al. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12944-8. doi: 10.1073/pnas.94.24.12944. Proc Natl Acad Sci U S A. 1997. PMID: 9371780 Free PMC article.
Genetic analysis of hydroxymethylglutaryl-coenzyme A reductase regulated degradation.
Hampton RY. Hampton RY. Curr Opin Lipidol. 1998 Apr;9(2):93-7. doi: 10.1097/00041433-199804000-00003. Curr Opin Lipidol. 1998. PMID: 9559264 Review.
Sequence determinants for regulated degradation of yeast 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein.
Gardner R, Cronin S, Leader B, Rine J, Hampton R. Gardner R, et al. Mol Biol Cell. 1998 Sep;9(9):2611-26. doi: 10.1091/mbc.9.9.2611. Mol Biol Cell. 1998. PMID: 9725915 Free PMC article.
A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes.
Gardner RG, Hampton RY. Gardner RG, et al. Among authors: hampton ry. J Biol Chem. 1999 Oct 29;274(44):31671-8. doi: 10.1074/jbc.274.44.31671. J Biol Chem. 1999. PMID: 10531376
A 'distributed degron' allows regulated entry into the ER degradation pathway.
Gardner RG, Hampton RY. Gardner RG, et al. Among authors: hampton ry. EMBO J. 1999 Nov 1;18(21):5994-6004. doi: 10.1093/emboj/18.21.5994. EMBO J. 1999. PMID: 10545111 Free PMC article.
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