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Two disparate ligand-binding sites in the human P2Y1 receptor.
Zhang D, Gao ZG, Zhang K, Kiselev E, Crane S, Wang J, Paoletta S, Yi C, Ma L, Zhang W, Han GW, Liu H, Cherezov V, Katritch V, Jiang H, Stevens RC, Jacobson KA, Zhao Q, Wu B. Zhang D, et al. Among authors: han gw. Nature. 2015 Apr 16;520(7547):317-21. doi: 10.1038/nature14287. Epub 2015 Mar 30. Nature. 2015. PMID: 25822790 Free PMC article.
Structure of an agonist-bound human A2A adenosine receptor.
Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC. Xu F, et al. Among authors: han gw. Science. 2011 Apr 15;332(6027):322-7. doi: 10.1126/science.1202793. Epub 2011 Mar 10. Science. 2011. PMID: 21393508 Free PMC article.
Structural characterization of three novel hydroxamate-based zinc chelating inhibitors of the Clostridium botulinum serotype A neurotoxin light chain metalloprotease reveals a compact binding site resulting from 60/70 loop flexibility.
Thompson AA, Jiao GS, Kim S, Thai A, Cregar-Hernandez L, Margosiak SA, Johnson AT, Han GW, O'Malley S, Stevens RC. Thompson AA, et al. Among authors: han gw. Biochemistry. 2011 May 17;50(19):4019-28. doi: 10.1021/bi2001483. Epub 2011 Apr 21. Biochemistry. 2011. PMID: 21434688 Free PMC article.
Structure of the human histamine H1 receptor complex with doxepin.
Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Shimamura T, et al. Among authors: han gw. Nature. 2011 Jun 22;475(7354):65-70. doi: 10.1038/nature10236. Nature. 2011. PMID: 21697825 Free PMC article.
Crystal structure of a lipid G protein-coupled receptor.
Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, Reinhart G, Desale H, Clemons B, Cahalan SM, Schuerer SC, Sanna MG, Han GW, Kuhn P, Rosen H, Stevens RC. Hanson MA, et al. Among authors: han gw. Science. 2012 Feb 17;335(6070):851-5. doi: 10.1126/science.1215904. Science. 2012. PMID: 22344443 Free PMC article.
Structure of the human κ-opioid receptor in complex with JDTic.
Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, Stevens RC. Wu H, et al. Among authors: han gw. Nature. 2012 Mar 21;485(7398):327-32. doi: 10.1038/nature10939. Nature. 2012. PMID: 22437504 Free PMC article.
Structural basis for allosteric regulation of GPCRs by sodium ions.
Liu W, Chun E, Thompson AA, Chubukov P, Xu F, Katritch V, Han GW, Roth CB, Heitman LH, IJzerman AP, Cherezov V, Stevens RC. Liu W, et al. Among authors: han gw. Science. 2012 Jul 13;337(6091):232-6. doi: 10.1126/science.1219218. Science. 2012. PMID: 22798613 Free PMC article.
189 results