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Cytochrome P450 CYP716A53v2 catalyzes the formation of protopanaxatriol from protopanaxadiol during ginsenoside biosynthesis in Panax ginseng.
Han JY, Hwang HS, Choi SW, Kim HJ, Choi YE. Han JY, et al. Plant Cell Physiol. 2012 Sep;53(9):1535-45. doi: 10.1093/pcp/pcs106. Epub 2012 Aug 7. Plant Cell Physiol. 2012. PMID: 22875608
Production of the dammarene sapogenin (protopanaxadiol) in transgenic tobacco plants and cultured cells by heterologous expression of PgDDS and CYP716A47.
Chun JH, Adhikari PB, Park SB, Han JY, Choi YE. Chun JH, et al. Plant Cell Rep. 2015 Sep;34(9):1551-60. doi: 10.1007/s00299-015-1806-9. Epub 2015 May 17. Plant Cell Rep. 2015. PMID: 25981048
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