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Crystal structure-based comparison of two NAMPT inhibitors.
Zhang SL, Xu TY, Yang ZL, Han S, Zhao Q, Miao CY. Zhang SL, et al. Among authors: han s. Acta Pharmacol Sin. 2018 Feb;39(2):294-301. doi: 10.1038/aps.2017.80. Epub 2017 Aug 31. Acta Pharmacol Sin. 2018. PMID: 28858298 Free PMC article.
Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.
Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B. Yang Z, et al. Among authors: han s. Nature. 2018 Apr;556(7702):520-524. doi: 10.1038/s41586-018-0046-x. Epub 2018 Apr 18. Nature. 2018. PMID: 29670288 Free PMC article.
Structural basis of Gs and Gi recognition by the human glucagon receptor.
Qiao A, Han S, Li X, Li Z, Zhao P, Dai A, Chang R, Tai L, Tan Q, Chu X, Ma L, Thorsen TS, Reedtz-Runge S, Yang D, Wang MW, Sexton PM, Wootten D, Sun F, Zhao Q, Wu B. Qiao A, et al. Among authors: han s. Science. 2020 Mar 20;367(6484):1346-1352. doi: 10.1126/science.aaz5346. Science. 2020. PMID: 32193322
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide.
Chang R, Zhang X, Qiao A, Dai A, Belousoff MJ, Tan Q, Shao L, Zhong L, Lin G, Liang YL, Ma L, Han S, Yang D, Danev R, Wang MW, Wootten D, Wu B, Sexton PM. Chang R, et al. Among authors: han s. J Biol Chem. 2020 Jul 10;295(28):9313-9325. doi: 10.1074/jbc.RA120.013793. Epub 2020 May 5. J Biol Chem. 2020. PMID: 32371397 Free PMC article.
Structural basis for ligand recognition of the neuropeptide Y Y2 receptor.
Tang T, Hartig C, Chen Q, Zhao W, Kaiser A, Zhang X, Zhang H, Qu H, Yi C, Ma L, Han S, Zhao Q, Beck-Sickinger AG, Wu B. Tang T, et al. Among authors: han s. Nat Commun. 2021 Feb 2;12(1):737. doi: 10.1038/s41467-021-21030-9. Nat Commun. 2021. PMID: 33531491 Free PMC article.
Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, Zhou Y, Pin JP, Rondard P, Liu H, Liu J, Sun F, Wu B, Zhao Q. Du J, et al. Among authors: han s. Nature. 2021 Jun;594(7864):589-593. doi: 10.1038/s41586-021-03641-w. Epub 2021 Jun 16. Nature. 2021. PMID: 34135509
Structures of Gi-bound metabotropic glutamate receptors mGlu2 and mGlu4.
Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, Liu J, Yang D, Wang MW, Zhao Q, Wu B. Lin S, et al. Among authors: han s. Nature. 2021 Jun;594(7864):583-588. doi: 10.1038/s41586-021-03495-2. Epub 2021 Jun 16. Nature. 2021. PMID: 34135510
Structures of the human cholecystokinin receptors bound to agonists and antagonists.
Zhang X, He C, Wang M, Zhou Q, Yang D, Zhu Y, Feng W, Zhang H, Dai A, Chu X, Wang J, Yang Z, Jiang Y, Sensfuss U, Tan Q, Han S, Reedtz-Runge S, Xu HE, Zhao S, Wang MW, Wu B, Zhao Q. Zhang X, et al. Among authors: han s. Nat Chem Biol. 2021 Dec;17(12):1230-1237. doi: 10.1038/s41589-021-00866-8. Epub 2021 Sep 23. Nat Chem Biol. 2021. PMID: 34556863
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