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A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. Osaka IDDM Study Group.
Imagawa A, Hanafusa T, Miyagawa J, Matsuzawa Y. Imagawa A, et al. Among authors: hanafusa t. N Engl J Med. 2000 Feb 3;342(5):301-7. doi: 10.1056/NEJM200002033420501. N Engl J Med. 2000. PMID: 10655528
Immunohistologic studies of pancreatic-biopsy specimens from three patients with negative tests for glutamic acid decarboxylase autoantibodies and low glycosylated hemoglobin values revealed T-lymphocyte-predominant infiltrates in the exocrine pancreas but no insulitis and …
Immunohistologic studies of pancreatic-biopsy specimens from three patients with negative tests for glutamic acid decarboxylase autoantibodi …
Three new mutations in the hepatocyte nuclear factor-1alpha gene in Japanese subjects with diabetes mellitus: clinical features and functional characterization.
Yoshiuchi I, Yamagata K, Yang Q, Iwahashi H, Okita K, Yamamoto K, Oue T, Imagawa A, Hamaguchi T, Yamasaki T, Horikawa Y, Satoh T, Nakajima H, Miyazaki J, Higashiyama S, Miyagawa J, Namba M, Hanafusa T, Matsuzawa Y. Yoshiuchi I, et al. Among authors: hanafusa t. Diabetologia. 1999 May;42(5):621-6. doi: 10.1007/s001250051204. Diabetologia. 1999. PMID: 10333057
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.
Hotta K, Funahashi T, Arita Y, Takahashi M, Matsuda M, Okamoto Y, Iwahashi H, Kuriyama H, Ouchi N, Maeda K, Nishida M, Kihara S, Sakai N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y. Hotta K, et al. Among authors: hanafusa t. Arterioscler Thromb Vasc Biol. 2000 Jun;20(6):1595-9. doi: 10.1161/01.atv.20.6.1595. Arterioscler Thromb Vasc Biol. 2000. PMID: 10845877
Identification of missense mutations in the hepatocyte nuclear factor-3beta gene in Japanese subjects with late-onset Type II diabetes mellitus.
Zhu Q, Yamagata K, Yu L, Tomura H, Yamada S, Yang Q, Yoshiuchi I, Sumi S, Miyagawa J, Takeda J, Hanafusa T, Matsuzawa Y. Zhu Q, et al. Among authors: hanafusa t. Diabetologia. 2000 Sep;43(9):1197-200. doi: 10.1007/s001250051512. Diabetologia. 2000. PMID: 11043867
Macrophages and dendritic cells infiltrating islets with or without beta cells produce tumour necrosis factor-alpha in patients with recent-onset type 1 diabetes.
Uno S, Imagawa A, Okita K, Sayama K, Moriwaki M, Iwahashi H, Yamagata K, Tamura S, Matsuzawa Y, Hanafusa T, Miyagawa J, Shimomura I. Uno S, et al. Among authors: hanafusa t. Diabetologia. 2007 Mar;50(3):596-601. doi: 10.1007/s00125-006-0569-9. Epub 2007 Jan 13. Diabetologia. 2007. PMID: 17221211
We examined the involvement of TNF-alpha and IL-1beta, as well as of T cells, macrophages and dendritic cells, in the destruction of beta cells in patients with recent-onset type 1 diabetes. ...TNF-alpha was detected in 25.0 (4.3-46.9)% of macrophages and 11.8 (0-40.0)% of …
We examined the involvement of TNF-alpha and IL-1beta, as well as of T cells, macrophages and dendritic cells, in the destruction of …
Pancreatic beta and alpha cells are both decreased in patients with fulminant type 1 diabetes: a morphometrical assessment.
Sayama K, Imagawa A, Okita K, Uno S, Moriwaki M, Kozawa J, Iwahashi H, Yamagata K, Tamura S, Matsuzawa Y, Hanafusa T, Miyagawa J, Shimomura I. Sayama K, et al. Among authors: hanafusa t. Diabetologia. 2005 Aug;48(8):1560-4. doi: 10.1007/s00125-005-1829-9. Epub 2005 Jul 1. Diabetologia. 2005. PMID: 15991022
Identification of a novel variant in the phosphoenolpyruvate carboxykinase gene promoter in Japanese patients with type 2 diabetes.
Horikawa Y, Yamasaki T, Nakajima H, Shingu R, Yoshiuchi I, Miyagawa J, Namba M, Hanafusa T, Matsuzawa Y. Horikawa Y, et al. Among authors: hanafusa t. Horm Metab Res. 2003 May;35(5):308-12. doi: 10.1055/s-2003-41307. Horm Metab Res. 2003. PMID: 12916001
Analysis of a non-functional HNF-1alpha (TCF1) mutation in Japanese subjects with familial type 1 diabetes.
Yoshiuchi I, Yamagata K, Yoshimoto M, Zhu Q, Yang Q, Nammo T, Uenaka R, Kinoshita E, Hanafusa T, Miyagawa Ji, Matsuzawa Y. Yoshiuchi I, et al. Among authors: hanafusa t. Hum Mutat. 2001 Oct;18(4):345-51. doi: 10.1002/humu.1196. Hum Mutat. 2001. PMID: 11668618
Mutation screening of the hepatocyte nuclear factor (HNF)-6 gene in Japanese subjects with diabetes mellitus.
Zhu Q, Yamagata K, Tsukahara Y, Yang Q, Liu W, Hanafusa T, Miyagawa J, Matsuzawa Y. Zhu Q, et al. Among authors: hanafusa t. Diabetes Res Clin Pract. 2001 Jun;52(3):171-4. doi: 10.1016/s0168-8227(01)00222-4. Diabetes Res Clin Pract. 2001. PMID: 11323086
Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion.
Yamamoto K, Miyagawa J, Waguri M, Sasada R, Igarashi K, Li M, Nammo T, Moriwaki M, Imagawa A, Yamagata K, Nakajima H, Namba M, Tochino Y, Hanafusa T, Matsuzawa Y. Yamamoto K, et al. Among authors: hanafusa t. Diabetes. 2000 Dec;49(12):2021-7. doi: 10.2337/diabetes.49.12.2021. Diabetes. 2000. PMID: 11118003
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